Publications by authors named "N Bertille"
Amantadine use in the French prospective NS-Park cohort.
J Neural Transm (Vienna)
July 2024
Article Synopsis
- The study aimed to evaluate the use of amantadine in patients with Parkinson's disease (PD) and its effectiveness in treating levodopa-induced dyskinesia (LIDs).
- It found that 12.6% of PD patients in the French NS-Park cohort were using amantadine, primarily younger patients with more severe symptoms and higher doses of levodopa.
- The results indicated that starting amantadine led to significant improvements in LIDs and motor fluctuations among new users compared to those who had never used the drug.
Article Synopsis
- - The study aimed to identify which subgroups of children with congenital heart defects (CHD) are at risk for impaired quality of life (QoL) by analyzing their medical and surgical treatments by age 8.
- - Results showed that children who received palliative repair had significantly lower QoL scores, both self-reported and parent-reported, compared to other subgroups, indicating a substantial impact on their well-being.
- - Children who underwent complete repair after age 3 also reported lower QoL, while those with complete repair before age 3 had a smaller decrease in self-reported QoL, suggesting that the age at intervention may affect long-term QoL outcomes.
Objective: To evaluate the respiratory outcome in children with congenital heart disease (CHD), considering recent management procedures and the CHD pathophysiology.
Design And Setting: Clinical and functional respiratory outcome were evaluated in 8-year-old children with isolated CHD followed up from birth in the prospective population-based EPICARD cohort.
Patients: Children were assigned to two groups, based on the pathophysiology of the CHD: CHDs with left-to-right shunt (n = 212) and CHDs with right outflow tract obstruction (n = 113).
Background: To examine disparities by maternal place of birth in the opportunity to make an informed choice about Down syndrome screening, in France, where the national guidelines recommend that physicians offer it to all pregnant women.
Methods: We used population-based data from the nationally representative French Perinatal Surveys in 2010 and 2016 (N=24,644 women) to analyze the opportunity for an informed choice for prenatal screening, measured by a composite indicator.
Results: Among the 24 644 women in the study, 20 612 (83.
EUROCAT is a European network of population-based congenital anomaly (CA) registries. Twenty-one registries agreed to participate in the EUROlinkCAT study to determine if reliable information on the survival of children born with a major CA between 1995 and 2014 can be obtained through linkage to national vital statistics or mortality records. Live birth children with a CA could be linked using personal identifiers to either their national vital statistics (including birth records, death records, hospital records) or to mortality records only, depending on the data available within each region.
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