Environ Sci Pollut Res Int
October 2024
This study investigates the adsorption of pollutants with different chemical structures; organic Naphtol Green B (NGB) dye and copper on a nanocomposite material with a hexagonal structure of the SBA-15 type. This research is divided into two main parts: the first carries out the synthesis of SBA-15 (Santa Barbra Amourphous) and its derivatives phases functionalized by 3-aminopropyl-triethoxylane (APTES) and calcined at 823 K. The second part presents the influence of the adsorption conditions on the adsorption efficiency of NGB dye and copper.
View Article and Find Full Text PDFValganciclovir, the ganciclovir prodrug, is an antiviral agent used to prevent cytomegalovirus infection in renal transplant children. Therapeutic drug monitoring is still necessary to ensure optimal therapeutic area under the concentration-time curve from 0 to 24 h (AUC) of 40 to 60 μg·h/mL since valganciclovir presents a high pharmacokinetic variability. To calculate ganciclovir AUC with the trapezoidal method, 7 samples are needed.
View Article and Find Full Text PDFAntimicrob Agents Chemother
September 2019
Background: Valganciclovir, the ganciclovir prodrug, is an antiviral agent administered orally to prevent or treat cytomegalovirus infection in solid organ transplant recipients. Dosing regimen of valganciclovir is still controversial in children, as the number of patients reaching the Area Under the Curve at steady state (AUC) target (40 - 60 mg.h/L) remains highly variable.
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