Publications by authors named "N Ben Fadhel"

Article Synopsis
  • * Using a nonparametric approach, the model examined how factors like age and kidney function (creatinine clearance) affected drug distribution and clearance.
  • * Results showed that the model accurately predicts vancomycin levels, highlighting the need for personalized dosing to ensure optimal effectiveness and safety for patients with varying degrees of renal impairment.
View Article and Find Full Text PDF

Purpose: The safety profile of methimazole (MMI) seems to be better than propylthiouracil in the management of hyperthyroidism. It is therefore advisable to use IMM as the first choice in Graves' patients. It is important to keep this drug in patients regardless of minor side effects.

View Article and Find Full Text PDF

DRESS related to first-line antituberculosis drugs (ATD) is a challenging diagnosis. With a long-lasting combined treatment of 4-concomitantly administrated drugs, identification of the culprit drug remains difficult and may expose patients to treatment interruption and affect their outcome. A 42-year-old female, treated with isoniazid, rifampicin, pyrazinamide and ethambutol for multifocal tuberculosis, developed, 40 days later, hyperthermia, facial edema, cervical lymphadenopathy and generalized exanthema.

View Article and Find Full Text PDF