Publications by authors named "N Beaupre"
Article Synopsis
- The study aimed to compare the effectiveness of 5 mg vs. 10 mg droperidol for treating acute agitation in emergency department patients.
- A total of 11,568 adult patients were analyzed, with 10,293 receiving 5 mg and 1,275 receiving 10 mg of droperidol, finding that 14.8% of patients on the 10 mg dose needed additional sedation compared to 9.6% on the 5 mg dose.
- The results suggest that the 5 mg dose may be more effective, as it led to lower rates of rescue sedation within one hour.
We have investigated the relationship between collagenase production, cell shape and stimulatory factors in cell culture. In a homogeneous culture of primary rabbit corneal stromal cells, shape change induced by a variety of agents was not effective in stimulating collagenase secretion. Only in the presence of a biologically active cytokine or phorbol myristate acetate was a correlation seen between changes in cell shape (induced by a second agent) and collagenase secretion by these primary cells.
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