Publications by authors named "N Bayle"

Article Synopsis
  • Tremor is the most common movement disorder, and while oral medications often have limited effectiveness due to side effects, botulinum toxin (BT) shows promise for improving upper limb function, although strong evidence is still lacking.
  • A systematic review analyzed existing studies on BT for upper-limb tremor, finding only eight randomized controlled trials and seven open-label studies with small sample sizes, indicating that tailored injections based on individual needs lead to better outcomes.
  • While BT injections can improve functionality, they may cause temporary weakness, particularly in wrist and finger movements; the review suggests optimizing injection techniques to minimize weakness and enhance effectiveness in treating tremors.
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Background: Movement smoothness is a potential kinematic biomarker of upper extremity (UE) movement quality and recovery after stroke; however, the measurement properties of available smoothness metrics have been poorly assessed in this group. We aimed to measure the reliability, responsiveness and construct validity of several smoothness metrics.

Methods: This ancillary study of the REM-AVC trial included 31 participants with hemiparesis in the subacute phase of stroke (median time since stroke: 38 days).

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Objective: In patients with Parkinson's disease, limited sit-to-stand, walk and turn contribute to decreased independence and quality of life. The 20-meter Ambulation Test (AT20) evaluates walking a total of 20 m, over a 10-m distance, back and forth between 2 chairs, starting and ending in a seated position. The aim of this study was to evaluate test-retest and inter-rater reliability of the AT20 in patients with Parkinson's disease.

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Backgound: Metrics for movement smoothness include the number of zero-crossings on the acceleration profile (N0C), the log dimensionless jerk (LDLJ), the normalized averaged rectified jerk (NARJ) and the spectral arc length (SPARC). Sensitivity to the handedness and movement type of these four metrics was compared and correlations with other kinematic parameters were explored in healthy subjects.

Methods: Thirty-two healthy participants underwent 3D upper limb motion analysis during two sets of pointing movements on each side.

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