Long term effects of gamma radiation on inflammatory and apoptotic biomarkers in nuclear medicine staff.

Background: Gamma radiation at low doses might have potential health effects in long-term exposure. The current study was aimed to search cell death pathway and inflammatory biomarkers in nuclear medicine workers with long-term exposure to gamma radiation.

Material And Methods: Fifty cases with a history of 10 years' exposure to gamma radiation and 30 normal individuals were included in the current study.

Monte Carlo Simulation for the Radixact™ Tomotherapy Linac Using EGSnrc.

Purpose: When exact information regarding the treatment head and initial electron beam is available, the Monte Carlo (MC) approach can properly simulate any linear accelerator. However, manufacturers seldom offer information such as the incident electron beam's energy, radial intensity (spot size), or angular spread. This research aims to forecast these features and verify an MC-simulated linear accelerator model using measurements.

Evaluation of the geometric and dosimetric accuracies of deformable image registration of targets and critical organs in prostate CBCT-guided adaptive radiotherapy.

Purpose: Kilovoltage cone beam computed tomography (kVCBCT)-guided adaptive radiation therapy (ART) uses daily deformed CT (dCT), which is generated automatically through deformable registration methods. These registration methods may perform poorly in reproducing volumes of the target organ, rectum, and bladder during treatment. We analyzed the registration errors between the daily kVCBCTs and corresponding dCTs for these organs using the default optical flow algorithm and two registration procedures.

The geometric and dosimetric accuracy of kilovoltage cone beam computed tomography images for adaptive treatment: a systematic review.

Objectives: To provide an overview and meta-analysis of different techniques adopted to accomplish kVCBCT for dose calculation and automated segmentation.

Methods: A systematic review and meta-analysis were performed on eligible studies demonstrating kVCBCT-based dose calculation and automated contouring of different tumor features. Meta-analysis of the performance was accomplished on the reported γ analysis and dice similarity coefficient (DSC) score of both collected results as three subgroups (head and neck, chest, and abdomen).

Evaluation of Anticancer and Cytotoxic Effects of Genistein on PC3 Prostate Cell Line under Three-Dimensional Culture Medium.

Background: Prostate cancer is a major cause of disease and mortality among men. Genistein (GNT) is an isoflavone found naturally in legumes. Isoflavones, a subset of phytoestrogens, are structurally similar to mammalian estrogens.