Modulation of phagocytic activity of blood polynuclear leukocytes with ozonized physiological saline.

We studied the effect of ozonized physiological saline on phagocytic properties of polymorphonuclear neutrophilic leukocytes from dog blood. Intravenous infusion of the examined doses of ozonized saline stimulated phagocytosis. Repeated intravenous infusion (48 h after) of the same dose was followed by a significant decrease in phagocytic capacity of polynuclears.

Redox status of rats during treatment by ozonated saline according to different protocols.

Repeated daily injections of ozonated saline to intact rats significantly modified their redox status. Intensification of free-radical processes paralleled by suppression of the antioxidant system creates prerequisites for failure of adaptation and compensation mechanisms of homeostasis.