Each hour injures, the last one kills.

The haemorrhage of psychiatrists from the NSW state-funded mental health system parallels losses throughout Australia, and internationally. The lack of workforce cripples the capacity to provide adequate care. There has been persistently neglectful under-resourcing of the care of people with severe mental illness.

Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials.

Background: Chronic coronary syndromes (CCS) is a common clinical condition that increases the risk of cardiovascular events at any time. Tongxinluo capsules (TXL) are widely used in China for treating CCS.

Objectives: To systematically evaluate the therapeutic effects and safety of adding TXL to Western medical treatment (WM) for CCS.

A metal-trap tests and refines blueprints to engineer cellular protein metalation with different elements.

It has been challenging to test how proteins acquire specific metals in cells. The speciation of metalation is thought to depend on the preferences of proteins for different metals competing at intracellular metal-availabilities. This implies mis-metalation may occur if proteins become mis-matched to metal-availabilities in heterologous cells.

Light-dependent variations in fatty acid profiles and gene expression in Antarctic microalgal cultures.

Photosynthetic eukaryotic microalgae are key primary producers in the Antarctic sea ice environment. Anticipated changes in sea ice thickness and snow load due to climate change may cause substantial shifts in available light to these ice-associated organisms. This study used a laboratory-based experiment to investigate how light levels, simulating different sea ice and snow thicknesses, affect fatty acid (FA) composition in two ice associated microalgae species, the pennate diatom Nitzschia cf.

Polarization Upends Convention: Halogen Bonding Propensities of Main Group Halides.

The propensities for sigma hole bonding by halogen atoms bonded to central atoms below period 2 in the periodic table remain to be systematically examined. Using iodine as our reference halogen atom, a comprehensive analysis of the tendencies for halogen and other forms of significant sigma hole bonding by simple compounds of main group atoms from H to At is accomplished. An examination of the structure and bonding of complexes formed by those iodine-substituted main group compounds and sigma donating bases (ammonia and trimethylamine) is performed to probe the viability of halogen bonding by heavy main group RM-I compounds in particular, given the historic focus on period 2.