Office nail fold capillary microscopy using ophthalmoscope.

A method for performing capillary microscopy using an ophthalmoscope is described. Using this technic, we examined 130 patients with various connective tissue diseases. As in prior studies, four patterns could be discerned; scleroderma (SD) pattern, lupus erythematosus (LE) pattern, normal pattern, and a nonspecific pattern.

Familial lupus erythematosus.

The child of a woman with discoid lupus erythematosus (DLE) had lesions of DLE develop at the age of 2 months. The original lesions persisted and new lesions continued to develop to date; the child is now 28 months old. In a second child, now 11 months old, a probable lupus erythematosus rash developed at 1 week of age.