: Patients with locally advanced rectal cancer (LARC) treated by neoadjuvant chemoradiotherapy (nCRT) may experience pathological complete response (pCR). Tools that can identify pCR are required to define candidates suitable for the watch and wait (WW) strategy. Automated image analysis is used for predicting clinical aspects of diseases.
View Article and Find Full Text PDFBackground: Conflicting studies have investigated the association between obesity, metabolic and bariatric surgery (MBS), and cancer.
Objectives: Our study aimed at elucidating the trends in cancer incidence that are related to obesity and weight loss managed through MBSs, like Colo-rectal, breast, uterine, and esophageal cancer.
Setting: We conducted a search using PubMed, Embase, and the Cochrane Library electronic databases through May 2020.
Local surgical excision of T1 rectal adenocarcinoma is a well-established approach. Yet, there are still open questions regarding the recurrence rates and its risk factors. A retrospective multicenter study including all patients who underwent local excision of early rectal cancer with an open or MIS approach and had a T1 lesion from 2010 to 2020 in six academic centers.
View Article and Find Full Text PDFBackground: German hospitals are legally obliged to implement digital patient portals within the next years. Systematic reviews show that the use of patient portals may be associated with improved patient-centeredness and workflows. However, mandatory digital healthcare innovations are sometimes not used by the target group as planned or even completely rejected.
View Article and Find Full Text PDFBackground: Optic disc edema is a feature of many ophthalmic and neurologic conditions. It remains an underappreciated feature of birdshot chorioretinitis (BSCR), leading to delay in diagnosis and treatment. The purpose of our study was to identify clinical features that are concomitant with optic disc edema and suggest a diagnosis of BSCR.
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