Applicability of a serodiagnostic line blot for idiopathic inflammatory myopathy: the muscle biopsy is not all.

Introduction: Differential diagnosis of rare idiopathic inflammatory myopathies (IIM) is mainly based on clinical aspects, muscle biopsy analysis, and auxiliary assays that determine myositis-specific and associated autoantibodies (MSA and MAA). While MSAs are considered specific for their respective IIM subclass, MAAs can be present in more than one subclass and in other conditions. This study compares results of a multispecific line blot assay with the final diagnosis of IIM patients based on clinical features and muscle biopsy to draw conclusions for the test's applicability in the diagnostic workflow.

Pregnancy outcomes in women with gestational diabetes mellitus by models of care: a retrospective cohort study.

Objective: To compare birth outcomes of women with gestational diabetes mellitus (GDM) with background obstetric population, stratified by models of care.

Design: Retrospective cohort study.

Setting: A tertiary referral centre in Sydney, Australia.

The relationship between falling insulin requirements and serial ultrasound measurements in women with preexisting diabetes: a prospective cohort study.

Introduction: A large fall in insulin requirements (FIR) in women with diabetes is associated with adverse clinical outcomes but previous studies have not examined its relation with serial ultrasound parameters.

Objective: To determine whether FIR is associated with alteration in umbilical artery Doppler parameters and fetal growth restriction (FGR) in women with preexisting diabetes.

Methods: Serial obstetric Doppler ultrasounds were conducted 2 weekly from 28 weeks gestation in women with Type 1 and Type 2 diabetes who were being treated with insulin.

Aspirin and pre-eclampsia prevention in women with pre-existing diabetes: a retrospective study.

Background: Aspirin is routinely prescribed in high-risk pregnancies to prevent pre-eclampsia; however, there is a paucity of data in women with pre-existing diabetes.

Aims: To assess the efficacy and safety of aspirin in women with pre-existing diabetes in preventing pre-eclampsia.

Methods: A retrospective review of women with pre-existing diabetes who attended antenatal clinics in a tertiary referral hospital between 2013 and 2019 was conducted.

Postpartum Seizure and Subarachnoid Haemorrhage Secondary to Moyamoya Disease.

Postpartum seizures secondary to subarachnoid haemorrhage (SAH) are rare. The incidence of pregnancy-related SAH is increasing and is highest during the delivery and postpartum periods. While there have been cases in the literature of SAH occurring postpartum, very few are associated with Moyamoya disease.