Publications by authors named "N B Anthony"
Study Objective: We performed a systematic review and Bayesian network meta-analysis to determine which pharmacologic therapies are relatively more effective and safer for migraine in adult patients who present to the emergency department (ED).
Methods: We searched MEDLINE, Embase, and Web of Science from inception to February 9, 2024. Eligible studies were randomized controlled trials that enrolled adult participants presenting to ED with migraine and compared one pharmacologic therapy to another or placebo.
Cancer cells exhibit a remarkable resilience to cytotoxic stress, often adapting through transcriptional changes linked to alterations in chromatin structure. In several types of cancer, these adaptations involve epigenetic modifications and restructuring of topologically associating domains (TADs). However, the underlying principles by which chromatin architecture facilitates such adaptability across different cancers remain poorly understood.
View Article and Find Full Text PDFHeart failure (HF) has become a global health threat, necessitating the development of novel treatment options to address this crisis. Sodium-glucose co-transporter-2 (SGLT2) inhibitors, such as dapagliflozin, may offer significant advantages in the treatment of HF, particularly in patients with reduced ejection fraction (HFrEF). This systematic review combines the findings from clinical studies to evaluate the safety and effectiveness of dapagliflozin in HF patients.
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- In 2022, 10.2% of fatal overdoses were linked to individuals facing homelessness or housing instability, with a growing concern over stimulant involvement in these overdoses in the U.S.
- Researchers in Kentucky analyzed stimulant-involved fatal overdoses from 2017 to 2021, linking records from a drug overdose surveillance system to electronic health records to assess housing status.
- Of the 313 overdose cases studied, initially only 10.5% were identified with housing instability, but after further data analysis, this figure rose to 41.5%, indicating that better data connections could enhance overdose surveillance and public health responses.