Publications by authors named "N Auger"
Introduction: Preeclampsia is associated with acute neurological complications during pregnancy, but the subsequent risk of developing a neurological disorder is unclear. We determined if preeclampsia was associated with the long-term risk of neurological morbidity.
Methods: We conducted a longitudinal cohort study of 1,460,098 pregnant women with and without preeclampsia in Quebec, Canada, between 1989 and 2023.
Article Synopsis
- This study examined how postpartum preeclampsia affects maternal and neonatal outcomes using data from over 1.3 million pregnancies in Quebec from 2006 to 2022.
- Postpartum preeclampsia was less common than antepartum preeclampsia but was linked to higher risks of preterm birth, placental abruption, and severe maternal complications.
- The research suggests that women who experience postpartum preeclampsia should have their blood pressure monitored for up to six weeks after delivery to identify any adverse effects.
Article Synopsis
- Next-generation sequencing (NGS) has helped uncover genetic causes of primary ovarian insufficiency (POI), while the reasons for diminished ovarian reserve (DOR) are less understood.
- A 14-year-old patient with isolated DOR was found to have two frameshift mutations in the BRCA1 gene, but surprisingly showed no signs of Fanconi anemia (FA).
- Despite the absence of FA symptoms, the patient's cells exhibited high chromosomal fragility, and studies indicated a shortened version of the BRCA1 protein was produced, suggesting that BRCA1 is crucial for ovarian health and functioning.
Background Tumor fraction (TF) at liquid biopsy is a potential noninvasive marker for tumor burden, but validation is needed. Purpose To evaluate TF as a potential surrogate for tumor burden, assessed at contrast-enhanced CT across diverse metastatic cancers. Methods This retrospective monocentric study included patients with cancer and metastatic disease, with TF results and contemporaneous contrast-enhanced CT performed between January 2021 and January 2023.
View Article and Find Full Text PDFThe not-so-simple question of when or if to induce a term pregnancy.
Paediatr Perinat Epidemiol
November 2024