Publications by authors named "N Ascher"
Article Synopsis
- * It identifies four key challenges to promoting innovation in SoHO treatments and suggests concrete solutions, emphasizing the need for collaboration, sustainability, and transparency among stakeholders.
- * The document calls for improved regulatory frameworks that ensure global quality and safety standards for SoHO while encouraging a regulatory environment that respects altruistic donation and enhances accessibility for patients.
Small-for-size syndrome (SFSS) following living donor liver transplantation is a complication that can lead to devastating outcomes such as prolonged poor graft function and possibly graft loss. Because of the concern about the syndrome, some transplants of mismatched grafts may not be performed. Portal hyperperfusion of a small graft and hyperdynamic splanchnic circulation are recognized as main pathogenic factors for the syndrome.
View Article and Find Full Text PDFPost Living Donor Liver Transplantation Small-for-size Syndrome: Definitions, Timelines, Biochemical, and Clinical Factors for Diagnosis: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.
Alfred Wei Chieh Kow Jiang Liu Madhukar S Patel Eleonora De Martin Mettu Srinivas Reddy Nancy Ascher
Transplantation
October 2023
Article Synopsis
- * A Consensus Scientific committee, comprised of 106 members from 21 countries, conducted an in-depth literature review and reached recommendations regarding ideal graft-to-recipient weight ratios, monitoring portal pressure and flow, and diagnosing SFSS around postoperative day 7.
- * The committee proposed a new 3-grade severity stratification system to help clinicians identify patients at risk for SFSS early on, suggesting that further studies are necessary to validate this system.