Publications by authors named "N Arima"

A 63-year-old man, previously diagnosed with multiple autoimmune diseases, developed life-threatening bleeding after gastrectomy for stomach cancer. He survived due to treatment with factor XIII (FXIII) concentrates immediately after his FXIII antigen (Ag) level was reported to be < 5% of normal. Detailed examination by the Japanese Collaborative Research Group on autoimmune coagulation factor deficiencies revealed the presence of anti-FXIII-A and anti-FXIII-B subunit autoantibodies on immunoblot analyses, and thus autoimmune FXIII deficiency (AiF13D) was diagnosed based on the Japanese and international diagnostic criteria.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigated the use of high-sensitivity cardiac troponin T (hs-cTnT) as a diagnostic tool for wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) among outpatient individuals aged 70 and older in Japan.
  • - Out of 1,141 enrolled participants, 55 showed elevated hs-cTnT levels, leading to further examinations for a total of 33, with 2 men ultimately diagnosed with ATTRwt-CA.
  • - The findings suggest that hs-cTnT testing can effectively screen for undiagnosed ATTRwt-CA in primary care, identifying 9.1% of those with elevated levels and at least 0.18% in the overall
View Article and Find Full Text PDF

Common variable immunodeficiency (CVID) is a primary B cell immunodeficiency disorder. Symptoms do not develop immediately after birth, and patients are often diagnosed in childhood and adulthood. These patients often develop autoimmune diseases and malignant tumors.

View Article and Find Full Text PDF

Bleeding and thrombosis are common complications during immune thrombocytopenic purpura (ITP) treatment. There is a strong need to predict bleeding and thrombosis risks before ITP treatment to optimize therapy and appropriately manage these complications. We performed a retrospective cohort study of 120 patients with primary ITP to identify a biomarker to predict bleeding and thrombosis.

View Article and Find Full Text PDF

Background: There is insufficient information regarding the bleeding sites and surgical strategies of cardiac tamponade during catheter ablation for atrial fibrillation (AF).

Case Presentation: Of the five patients with cardiac tamponade, three required surgical intervention and two required pericardiocentesis. In the first case of three cardiac tamponades requiring surgical intervention, considering that the peripheral route was used, the catecholamines did not reach the heart, and due to unstable vital signs, venoarterial extracorporeal membrane oxygenation (VA-ECMO) was inserted.

View Article and Find Full Text PDF