Publications by authors named "N Araya"

Article Synopsis
  • The study investigates the effectiveness of testing cerebrospinal fluid (CSF) for anti-HTLV-1 antibodies in diagnosing HTLV-1-associated myelopathy (HAM), highlighting the diagnostic accuracy of various test kits.
  • It found that while CSF antibody levels were stable when refrigerated, they were affected by freeze-thaw cycles, leading to strong correlations in test results across different methods used on samples from 92 patients (69 with HAM, 23 carriers).
  • The results showed high diagnostic performance for HAM, with five test kits achieving 100% sensitivity and varying specificity, suggesting that these tests combined with clinical evaluation can improve HAM diagnosis.
View Article and Find Full Text PDF

Objectives: The purpose of this study was to investigate the relationship between patient demographics and potential intraoperative factors and delayed bone union in opening wedge high tibial osteotomy (OWHTO).

Patients And Methods: A retrospective review of 65 patients (37 females, 28 males; mean age: 60.1±10.

View Article and Find Full Text PDF

Objectives: Distinguishing human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy from hereditary spastic paraplegia in patients infected with HTLV-1 is challenging due to overlapping clinical symptoms. The aim of this study was to explore the possibility that hereditary spastic paraplegia is inherently present in patients diagnosed with HTLV-1-associated myelopathy.

Methods: We performed whole-genome sequencing on 315 unrelated patients registered in the HTLV-1-Associated Myelopathy patient registry "HAM-net," from 2013 to 2022 in Japan.

View Article and Find Full Text PDF
Article Synopsis
  • * Results indicated that the zeolite could achieve a high concentration of copper ions (27 g/L) within 30 minutes, and that the CuO NPs were well-dispersed in the material.
  • * The copper-saturated zeolite was effective against antibiotic-resistant bacteria and exhibited superior antibacterial effects compared to those with CuO NPs, suggesting its potential use in dental biomedical applications and as a bactericidal additive in 3D printing.
View Article and Find Full Text PDF

Background: Human T-cell leukemia virus type 1 (HTLV-1) causes HTLV-1-associated myelopathy (HAM), adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated uveitis, and pulmonary diseases. Although both HAM and ATL show proliferation of infected cells, their pathogeneses are quite different. In particular, the pathogenesis of HAM is characterized by hyperimmune responses to HTLV-1-infected cells.

View Article and Find Full Text PDF