Publications by authors named "N Andrade"
Importance: Early evidence from studies outside of oncology has suggested that cannabidiol (CBD) may have anxiolytic effects without neuropsychiatric risks. An understanding of oral CBD in patients with cancer-related anxiety is urgently needed.
Objective: To determine whether a single 400-mg oral dose of a US Food and Drug Administration-approved CBD improves clinical anxiety in an oncologic population.
Impact of chronic toxoplasmosis in pregnancy: Association between maternal IgG antibodies against T. gondii and neurocognitive development effects.
Neurotoxicology
December 2024
Toxoplasmosis presents notable hazards in the context of pregnancy, impacting the health of the mother and the neurodevelopment of the fetus via immune reactions and possible vertical transmission. The maternal immune response from chronic Toxoplasma gondii (T. gondii) infection may negatively influence fetal neurodevelopment.
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- Direct Oral Anticoagulants (DOACs) are commonly used for treating non-valvular atrial fibrillation (NVAF), but Percutaneous Left Atrial Appendage Occlusion (LAAO) is a new treatment method with uncertain safety and effectiveness compared to DOACs.
- A systematic review of ten studies involving over 18,500 patients found that LAAO is linked to lower all-cause and cardiovascular mortality rates, as well as a reduction in the composite outcomes of death, bleeding, and thromboembolic events.
- While LAAO showed trends toward reduced stroke or TIA events and lower bleeding rates compared to DOACs, no significant differences in thromboembolic events were observed.
Imaging aspects of maxillomandibular bone alterations in patients with multiple myeloma treated with bisphosphonates: A systematic review.
Imaging Sci Dent
September 2024
Article Synopsis
- - Multiple myeloma (MM) is a rare cancer often treated with bisphosphonates, which help reduce bone loss and prevent complications, and this study focused on identifying imaging patterns related to this treatment in MM patients.
- - The study reviewed six research articles involving 669 MM patients, of which 447 were treated with bisphosphonates like pamidronate and zoledronate; many patients developed medication-related osteonecrosis of the jaw (MRONJ), primarily affecting the mandible with specific radiographic features.
- - The findings highlight distinct radiographic patterns of bone lesions in MM patients undergoing bisphosphonate therapy, which are important for early diagnosis and improving treatment outcomes.
Pancreatic cancer (PC) is the ninth-leading cause of cancer-related deaths worldwide. Diabetic patients have an increased risk and mortality rates for PC. Sodium-glucose co-transporter 2 (SGLT2) inhibitors and metformin (Met) are widely used anti-diabetic medications.
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