Publications by authors named "N Aladangady"
Introduction: There is significant uncertainty regarding the role that anaemia or red blood cell transfusion (RBCT) plays in the development of gut injury in preterm infants. This study evaluated Near Infrared Spectroscopy (NIRS) together with a range of known biomarkers of gut inflammation to identify their relationship with anaemia and RBCT.
Method: A prospective observational study of preterm infants born at <30 weeks gestation was conducted from birth until either 36 weeks post conceptional age or discharge home.
Introduction: Hypoxic ischaemic encephalopathy (HIE), a condition where the brain does not receive enough oxygen and/or blood flow around the time of birth, is associated with significant morbidity and mortality. Systemic circulation may be affected due to poor myocardial function. The cochlear hair cells are vulnerable to changes in microcirculation, which may occur in HIE predisposing to hearing loss.
View Article and Find Full Text PDFBackground: Carbapenemase-producing (CPE) are a group of Gram-negative bacteria causing global concern due to their resistance to carbapenems. In this report, we detail the learning points from a CPE outbreak in a tertiary neonatal unit (NU) in the UK.
Methods: Routine surveillance screening (rectal swabs) of babies on the NU identified a potential cluster of CPE carriage.
Article Synopsis
- This study investigates the safety and effectiveness of whole-body hypothermia in neonates who have experienced mild hypoxic-ischemic encephalopathy (HIE), as existing data mainly focuses on cases of more severe illness.* -
- Conducted as a randomized clinical trial across six neonatal intensive care units in the UK and Italy, 101 eligible neonates were assigned to either normothermia or different durations of hypothermia (48 or 72 hours) based on their age after birth.* -
- The study primarily measures the concentration of thalamic N-acetyl aspartate through MRI to assess the impact of hypothermia on brain health, revealing specific outcomes in the treatment groups.*
Optimal cord management (OCM), defined as waiting at least 60 seconds (s) before clamping the umbilical cord after birth, is an evidence-based intervention that improves outcomes for both term and preterm babies. All major resuscitation councils recommend OCM for well newborns.National Neonatal Audit Programme (NNAP) benchmarking data identified our tertiary neonatal unit as a negative outlier with regard to OCM practice with only 12.
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