Publications by authors named "N Al Rifai"
Acoustic Droplet Vaporization Efficiency and Oxygen Scavenging in Whole Blood.
Ultrasound Med Biol
February 2025
Objective: Acoustic droplet vaporization (ADV) is the liquid-to-gas phase transition of perfluorocarbon (PFC) droplets to microbubbles upon ultrasound insonation. After ADV, gases dissolved in the surrounding fluid diffuse into microbubbles, enabling oxygen scavenging. Characterization of oxygen scavenging and transition efficiency (TE) in whole blood has so far been limited.
View Article and Find Full Text PDFBackground: High-sensitivity C-reactive protein (CRP), low-density lipoprotein (LDL) cholesterol, and lipoprotein(a) levels contribute to 5-year and 10-year predictions of cardiovascular risk and represent distinct pathways for pharmacologic intervention. More information about the usefulness of these biomarkers for predicting cardiovascular risk over longer periods of time in women is needed because early-life intervention represents an important risk-reduction method.
Methods: We measured high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) levels at baseline in 27,939 initially healthy U.
Article Synopsis
- Long-acting crystal suspensions of active pharmaceutical ingredients (API) involve a mixture of the API, water, and excipients to ensure a sustained release over time.
- PVP K30 was identified as the most effective excipient for stabilizing naproxen crystals, achieving a target crystal size of 1 to 15 μm by using ethanol and water in the process.
- A seven-stage diafiltration process successfully reduced the amount of PVP K30 present in the suspension without compromising crystal stability, demonstrating a significant decrease in the PVP-to-naproxen ratio.