Publications by authors named "N Al Haj Husain"
Background: Multiparametric cardiovascular magnetic resonance (CMR) has an emerging role in non-invasive surveillance of pediatric heart transplant recipients (PHTR). Higher myocardial T2, higher extracellular volume fraction (ECV), and late gadolinium enhancement (LGE) have been associated with adverse clinical outcomes in adult heart transplant recipients. This study's purpose was to investigate the prognostic value of CMR-derived T1- and T2-mapping, ECV, and LGE for clinical outcomes in PHTR.
View Article and Find Full Text PDFBackground: Down-Regulated in Adenoma (DRA) plays a critical role in intestinal chloride absorption and a decrease in its expression is a key event in diarrheal disorders. Recently, DRA has emerged as an Inflammatory Bowel Disease (IBD) susceptibility gene. Therefore, the strategies to upregulate DRA expression are potentially novel approaches to not only treat IBD-associated diarrhea but also gut inflammation.
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- Cardiomyopathy is a major cause of death in boys with Duchenne muscular dystrophy (DMD), and this study investigates cardiac function using cardiac magnetic resonance (CMR) imaging to compare DMD patients with healthy controls.
- The study involved 179 DMD patients and 96 healthy controls, focusing on measuring left ventricular (LV) function, with findings demonstrating significant differences in ventricular volumes and ejection rates, indicating compromised cardiac function in DMD patients.
- Results suggest that certain CMR filling and ejection indices correlate with increased mortality in DMD patients, highlighting the potential for these measures to serve as important prognostic tools.
Article Synopsis
- The text discusses a study comparing two surgical approaches, conventional multi-port laparoscopy (CL) and single-incision laparoscopic surgery (SILS), for patients undergoing Hartmann's reversal (HR), primarily after colostomy.
- A thorough online search led to the inclusion of two observational studies with 160 patients, revealing that SILS had a significantly shorter operative duration, while other outcomes like mortality and complications showed no significant differences.
- The conclusion indicates that, despite some limitations in the research, SILS is a quicker method with comparable safety and effectiveness to CL techniques.
Introduction: Recent studies have suggested that ambulatory management is feasible for acute uncomplicated diverticulitis (AUD); however, there is still no consensus regarding the most appropriate management settings. This study presents a multi-centre experience of managing patients presenting with AUD, specifically focusing on clinical outcomes and comparing ambulatory treatment with in-patient management.
Methods: A retrospective multi-centre study was conducted across four hospitals in the UK and included all adult patients with computed tomography (CT) confirmed (Hinchey grade 1a) acute diverticulitis over a 12-month period (January - December 2022).