Publications by authors named "N Acevedo"
Article Synopsis
- * The discovery of 26 B. tropicalis allergens, some cross-reactive with other mite species, complicates diagnosis and treatment options for allergies, though advancements in component-resolved diagnostics aid in this process.
- * Immunotherapy using B. tropicalis extracts is effectively implemented in various countries, but there is a challenge with the limited availability of standardized extracts, despite significant research contributions over the past five decades on allergen characterization and potential impacts of climate change.
Article Synopsis
- Peutz-Jeghers syndrome (PJS) is a rare genetic disorder that leads to intestinal polyps and skin pigmentation, with solitary polyps being very uncommon.
- A case study is presented of a 50-year-old woman with PJS who had dyspeptic symptoms and rectal bleeding, revealing a solitary polyps during an endoscopy.
- The study highlights the need for thorough diagnosis and treatment, stressing the importance of regular monitoring for potential cancer development in patients with PJS.
Article Synopsis
- - The study aimed to identify different asthma phenotypes in asthmatic children aged 7 to 17 years in Cartagena, Colombia, using T2 inflammation biomarkers like FeNO and eosinophil counts.
- - Of the 107 children assessed, 19.6% exhibited non-T2 inflammation (non-allergic asthma), while 71.9% were found to have allergic asthma, with 30.8% classified as high T2 allergic asthma due to elevated biomarker levels.
- - Results showed a significant correlation between FeNO and eosinophil levels, highlighting that both specific IgE testing and biomarker measurements are essential for accurately diagnosing high T2 asthma phenotypes in children.
Objective: To carry out a preliminary analysis on the Treg lymphocyte counts present in the peripheral blood of allergic asthmatic children from the city of Cartagena, Colombia, compared to healthy controls.
Methods: We compared cytometry counts of ten asthmatic patients (age 7-16 years) and seven healthy controls (6-12 years), recruited in the city of Cartagena. Peripheral blood samples were stained using Cytek's 14-color cFluor Immunoprofiling kit (Cytek cFluor Immunoprofiling Kit 14 Color RUO kit), and analyzed on a Northern Lights™ spectral cytometer (Cytek Biosciences, Fremont, CA, USA), to read 50.
Article Synopsis
- The study aimed to compare immune cell populations in the blood of infected (n=35) and uninfected (n=27) individuals from rural Bolívar, using specific diagnostic techniques and flow cytometry for analysis.
- Results showed no significant differences in age or sex between the two groups, with mild infections noted in cases and a slight decrease in neutrophil percentage among infected individuals, though the overall differences in immune cell types were minimal.
- The study was ethically approved, participants consented, and funding was provided through the Colombian Sistema General de Regalías.