Publications by authors named "N Abdejlil"
Article Synopsis
- - The study identified the first vancomycin-resistant Enterococcus (VREfs) strain in Tunisia from an 8-year-old patient with bone marrow issues, using whole-genome sequencing (WGS) after isolating it during a hospital stay.
- - The strain showed significant resistance levels, with minimum inhibitory concentrations of vancomycin >256 mg/L and teicoplanin at 16 mg/L, and was classified as the ST249 clone typically found in avian sources.
- - This report highlights a novel case where an initially vancomycin-susceptible strain acquired resistance via a plasmid that carried a transposon, aided by specific genetic mechanisms related to conjugation and CRISPR interference
Article Synopsis
- This study investigates vancomycin-resistant Enterococcus faecium (VREfm) in Tunisia, focusing on its molecular characteristics and the genetic factors behind its resistance.
- The research analyzed 80 VREfm isolates from hospitalized patients over six years, showing a significant increase in prevalence from 2% to 27%, all containing the vanA gene and common resistance genes like ermB and tetM.
- The findings highlight a concerning trend in VREfm's persistence and genetic variability due to horizontal gene transfer, emphasizing the complexity of its resistance mechanisms.
A 61-year-old woman presented with a 3-year history of painless soft-tissue mass on the right sole. The patient reported gradual growth, with a rapid increase in size over the past few months, leading to difficulty in walking. She had no history of past trauma.
View Article and Find Full Text PDFThe aim of our clinical image was to emphasize the value of a careful skin examination in the diagnosis of early-onset sarcoidosis in children.
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