[Response of the secretory glands of the stomach to peptide injection into the hypothalamus, caudate nucleus and amygdala].

In chronic experiments on dogs, microapplication of neurotensin into the hypothalamus or amygdala combined with histamin or pentagastrin stimulation of the stomach secretory function significantly reduced the stomach secretion. Microapplication of somatostatin into the hypothalamus or amygdala combined with i.v.

[Effect of somatostatin on gastric hydrochloric acid secretion and serum gastrin concentration in the dog].

I.v. administration of somatostatin (1.

[Effect of methionine-5-enkephalin retroanalog on gastric secretion].

Alteration of the enkephalin molecule by means of synthesis of peptide with opposite direction of peptide connections between residues of aminoacids (retro--methionin--5--enkephalin) entailed some changes of its action in respect to activity of the stomach secretory cells in dogs. Thus, for instance, the retroanalogue methionin--5--enkephalin proved to be a more efficient activator of gastric secretion induced with pentagastrin.