[Effects of ultracaine on the local blood flow of the gum and on the development of cerebral seizures in experiment].

We have studied the effect of ultracaine DS forte on local blood flow of the rat gum as well as on the development of the convulsion activity of the brain at systemic injection. Experiments were carried out on 12 mongrel albino mail rats of 200-250 g weight. In the I group of animals under the light chloral hydrate anesthesia we studied the changes of local blood flow in the rat gum of lower jaw after ultracaine DS forte injection (right side) and the similar quantity of phisiological solution (left side).

[Effect of lidocaine and lidocaine with adrenaline on development of cerebral seizures].

Experiments were carried out on male albino rats of 200-250 g weight with bipolar electrodes implanted in neocortex, as well as in the right and the left dorsal hippocampus for the study of the effect of lidocaine and its combination with adrenaline on the electric activity of brain. On the fifth day from the implantation in the first group of animals 0,3 ml 2% lidocaine was injected intra-peritoneally and the electric activity from the above mentioned structures was registered. In the second group 0,3 ml 2% lidocaine with adrenaline was injected intra-peritoneally (1:100000).