Publications by authors named "N A Sinclair"

One regime of experimental particle-laden flow study involves ejecta microjets-often defined as a stream of micrometer-scale particles generated through shock interaction with a non-uniform surface and generally travel above 1 km/s. In order to capture the change in characteristics as a function of propagation time, we apply a multi-frame x-ray radiography platform to observe and track the jet transport dynamics. A synchrotron x-ray source allows us to perform quantitative analyses and comparisons between the eight images captured by the imaging system.

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The preoperative evaluation plays an important role in optimizing outcomes and minimizing morbidity for patients undergoing blepharoplasty. This article provides a detailed, systematic approach for the preoperative evaluation of patients undergoing upper and lower blepharoplasty. This article focuses on the critical steps of evaluating surgical blepharoplasty candidates to ensure optimal outcomes and high patient satisfaction, while minimizing risks and complications.

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Mucosal barrier tissues and their mucosal associated lymphoid tissues (MALT) are attractive targets for vaccines and immunotherapies due to their roles in both priming and regulating adaptive immune responses. The upper and lower respiratory mucosae, in particular, possess unique properties: a vast surface area responsible for frontline protection against inhaled pathogens but also simultaneous tight regulation of homeostasis against a continuous backdrop of non-pathogenic antigen exposure. Within the upper and lower respiratory tract, the nasal and bronchial associated lymphoid tissues (NALT and BALT, respectively) are key sites where antigen-specific immune responses are orchestrated against inhaled antigens, serving as critical training grounds for adaptive immunity.

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Background: This paper describes how First Nations Kidney Warriors (Aboriginal and Torres Strait Islander people living with kidney disease), dental hygienists, kidney health care professionals, an Aboriginal hostel accommodation manager and researchers co-designed an approach to improve oral health in South Australia. Kidney Warriors have strong connection to Country, Community and family that underpins health, wellbeing and approaches to research. However, significant colonisation, racism and marginalisation have impacted Kidney Warriors' social, cultural and financial determinants of health, leading to increased chronic conditions including kidney disease.

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Article Synopsis
  • - The study compares the time burden of subcutaneous (SC) versus intravenous (IV) drug administration of trastuzumab and pertuzumab in breast cancer patients, aiming to improve their quality of life during treatment.
  • - Results from 22 enrolled patients showed that SC administration significantly reduced the time patients spent in the treatment chair by an average of 61.8 minutes and total treatment experience time by 81.8 minutes compared to IV.
  • - The findings suggest that SC administration not only shortens patient time commitment but also enhances workflow efficiency for healthcare professionals, making the treatment process more manageable for patients.
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