Publications by authors named "N A Sandiford"
Does the duration of antibiotic treatment following one-stage treatment of infected total knee arthroplasty influence the eradication rate? A systematic review.
Arch Orthop Trauma Surg
December 2024
Purpose: The aim of this study was to perform a systematic review of the current literature to elucidate the optimal duration of systemic antibiotic therapy following one-stage revision TKA in the setting of PJI.
Methods: We conducted an electronic search in four databases including Medline (PubMed), Scopus, Web of Science, and Cochrane Central Register of Controlled Trials without any publication date, language or study design filter on October 1, 2022. The search strategy adhered to PRISMA guidelines and consisted of four main keywords categories which were knee arthroplasty or knee prosthesis, infection and one-stage/single-stage revision.
Article Synopsis
- Total hip and knee arthroplasty procedures on patients with previous periarticular surgeries (conversion arthroplasties) are complex and may involve higher complication risks, including unexpected positive cultures (UPC) and periprosthetic joint infections (PJI).
- A study reviewed 205 conversion arthroplasty cases from 2012 to 2018, finding that UPC occurred at rates akin to standard revision arthroplasties, with staphylococcal species being the most commonly isolated bacteria.
- The study concluded that while UPC are more common in conversion knee arthroplasties than in hips, UPC presence does not significantly increase the risk of developing PJI.
Purpose: Unexpected positive cultures are defined as a single positive culture in intraoperative samples taken during revision surgery after prosthetic joint infection was preoperatively ruled out. This study aims to determine the prevalence of unexpected positive cultures (UPC) in revision total knee arthroplasty (TKA) after unicompartmental knee arthroplasty (UKA). As a secondary objective, this study aims to compare the re-intervention rate in this specific group, between UPC and non-UPC patients.
View Article and Find Full Text PDFPurpose: Total knee arthroplasty (TKA) is a common orthopedic surgery, yet postoperative dissatisfaction persists in around 20% of cases. Robotic total knee arthroplasty (rTKA) promises enhanced precision, but its impact on patient satisfaction compared to conventional TKA remains controversial (cTKA). This systematic review aims to evaluate patient satisfaction post-rTKA and compare outcomes with cTKA.
View Article and Find Full Text PDFIntroduction: The purpose of this study was to evaluate the management and results of our standarized protocol for preoperative identification of MRSA colonisation in patients undergoing primary total hip and knee replacement procedures.
Methods: Following hospital protocol, between January 2016 and June 2019 37,745 patients awaiting elective joint replacement underwent a standardized questionnaire to assess the risk of MRSA infection, identifying patients requiring preoperative MRSA screening. An evaluation of the questionnaire identified effective questions for identifying infected patients.