A map of the rubisco biochemical landscape.

Rubisco is the primary CO-fixing enzyme of the biosphere, yet it has slow kinetics. The roles of evolution and chemical mechanism in constraining its biochemical function remain debated. Engineering efforts aimed at adjusting the biochemical parameters of rubisco have largely failed, although recent results indicate that the functional potential of rubisco has a wider scope than previously known.

Structural brain correlates of externalizing traits and symptoms in the IMAGEN sample.

The evidence supporting the presence of individual brain structure correlates of the externalizing spectrum (EXT) is sparse and mixed. To date, large-sample studies of brain-EXT relations have mainly found null to very small effects by focusing exclusively on either EXT-related personality traits (e.g.

Reactive and Proactive Aggression in Daily Life: An Exploratory Experience-Sampling Method Study.

Trait aggression is often separated into two functional dimensions: reactive and proactive tendencies. Reactive aggression is the tendency to engage in emotionally driven aggressive responses to perceived provocation, whereas proactive aggression is the tendency to engage in premeditated aggressive behaviors in the service of goal attainment. To date, the majority of empirical investigations examining these interrelated constructs have done so using cross-sectional data that have important limitations (e.

Psychosocial Function in Mild Cognitive Impairment: Social Participation is Associated With Cognitive Performance in Multiple Domains.

Psychosocial function is associated with cognitive performance cross-sectionally and cognitive decline over time. Using data from the COMPASS-ND study, we examined associations between psychosocial and cognitive function in 126 individuals with mild cognitive impairment, an at-risk group for Alzheimer's disease (AD). Psychosocial function was measured using questionnaires about mental health, social support, and social engagement.

Exploring the use of digital technology for injury prevention and self-management among recreational runners.

Objectives: Explore digital technology use among recreational runners in Wales and assess attitudes toward a proposed digital intervention for running-related injury (RRI) prevention and self-management.

Design: Exploratory survey.

Setting: Online questionnaire, closed questions distributed to runners over a 7 week period.