Publications by authors named "N A O'Rourke"

Background: Health and social care standards are multi-faceted interventions that promote quality and safe care in health systems. There is a need to apply evidence-based, rigorous and transparent methods when selecting strategies to support the implementation of standards. We aimed to develop an evidence- and theory-informed intervention to guide researchers in identifying appropriate implementation strategies and then selecting tailored support tools and actions for use when implementing a set of standards.

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Article Synopsis
  • - Identified four distinct clusters of adults with bipolar disorder (BD) based on BD symptoms and perceived cognitive errors, with a hypothesis suggesting that more symptoms and cognitive errors correlate with lower psychological well-being.
  • - The study involved 281 adults aged 19-81, revealing that those with more cognitive failures reported higher levels of both depression and hypo/mania symptoms, leading to lower self-efficacy and life satisfaction.
  • - Contrary to previous research, age differences in cognitive loss were not significant across the clusters, indicating that perceived cognitive errors negatively impact psychological well-being regardless of the participant's age.
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Several known biomarkers have been used to understand the physiological responses of humans to various short and long-term interventions such as exercise or dietary interventions. However, little exploratory work has been conducted to identify novel biomarkers in human saliva that could enable non-invasive physiological research to understand acute responses to interventions such as reducing sedentary time. The purpose of this study was to identify novel biomarkers in the saliva (cytokines, growth factors and vascular factors) that respond to prolonged (4 hours) and interrupted sitting (4 hours of sitting interrupted by 3 minutes of walking at 60% of maximal heart rate every 27 minutes) in young, healthy males and females.

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Background: National health and social care standards are complex, quality improvement interventions. Standards typically describe a process and/or outcome of safe, quality, person-centred care according to best evidence. Currently, there are 11 national standards that apply to diverse services in Ireland including residential centres, acute hospitals and rehabilitation and community inpatient healthcare services.

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