Publications by authors named "N A Nikuradze"

Microbiological investigation of 124 patients with acute conjunctivitis which were treated in one of Tbilisi policlinics in 2010-12 years, was performed; microbial structure containing 124 microbial strains of different species was detected. Namely, following species of microorganisms were isolated: S. aureus - 35 strains (28,2%), Str.

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The linear interrelation between Systemic Arterial Blood Pressure and local Cerebral Blood Flow has been shown in experiments on rats with induced experimental hepatic encephalopathy. This is evidence of complete malfunctioning of the mechanism of Cerebral Blood Flow Autoregulation. Quantitative comparison of local Cerebral Blood Flow intensity in control and experimental (Hepatic Encephalopathy) animals has shown significant increase of the basic level of cerebral blood flow in rats with induced Hepatic Encephalopathy (p<0,05).

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Existence of the autoregulation phenomenon in the blood supply system of the optic nerve has been established in the 1990; however, some of its quantitative and qualitative characteristics still require clarification. The goal of the present work was assessment of the lower margin in autoregulation of the blood supply of the optic nerve in the rabbit in conditions of attenuated level of perfusion pressure. Total of six adult rabbits weighing 2.

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Reference data on the function of renin-angiotensin-aldosterone system (RAAS) and pharmacological correction of its hyperactivity are summarized and analyzed in the paper. RAAS plays important role in the development and worsening of hypertension, facilitates proliferation of smooth muscle and heart cells. The hyperactivity of RAAS promotes the development of cardiovascular complications, such as myocardial infarction, stroke, increases cardiovascular mortality and morbidity.

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The experimental and clinical data concerning pathogenesis of the atherosclerosis are summarized and analyzed in this article. Major concepts that explain initiation and progressive growth of atherosclerosis such as lipid infiltrations, response to disturbing factors, "response on the keeping of particles" and inflammatory processes are discussed. These concepts are considered as base for integral theory of atherosclerosis according which the inflammatory process in atherosclerosis are the result of the universal response reaction of endothelium to the various disturbing risk factors.

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