PSYCHOLOGICAL FEATURES OF REHABILITATION OF HIV-INFECTED PATIENTS.

Unlabelled: The human immunodeficiency virus (HIV) is one of the major medical problems in the world. For almost forty years, it has had catastrophic effects on the body of infected people with variable pathogenesis of mortality. The purpose of the work is to analyse the importance of psychological assistance for the social adaptation of HIV-infected patients.

THE VALUE OF SERUM SEROMUCOID IN THE DIFFERENTIAL DIAGNOSIS OF BACTERIAL PNEUMONIA AND TUBERCULOSIS IN HIV-POSITIVE PATIENTS.

Objective: The aim: To optimize the differential diagnosis of bacterial pneumonia and tuberculosis in HIV-positive patients based on the value of serum seromucoid.

Patients And Methods: Materials and methods: The study included 77 HIV-positive patients with lung pathology. The 1st group consisted of 44 HIV-infected patients with BP; the 2nd group - of 33 patients with HIV/TB co-infection.

MORPHOLOGICAL EFFICACY EVALUATION OF GEL WITH CARBON DIOXIDE EXTRACT OF HOPS IN CASE OF COMPLICATED WOUND INFECTION ACNE VULGARIS.

Objective: The aim of the study is to reveal in the experiment the morphological features of the infected skin wounds healing, which are a manifestation of acne vulgaris severe and very severe forms, using a gel with carbon dioxide extract of hops.

Patients And Methods: Materials and methods: An experimental study was carried out on 80 male WAG rats of three months of age. The animals were divided into 9 groups.

Application of New Efficient Hoveyda-Grubbs Catalysts Comprising an N→Ru Coordinate Bond in a Six-Membered Ring for the Synthesis of Natural Product-Like Cyclopenta[]furo[2,3-]pyrroles.

The ring rearrangement metathesis (RRM) of a - diastereomer mixture of methyl 3-allyl-3a,6-epoxyisoindole-7-carboxylates derived from cheap, accessible and renewable furan-based precursors in the presence of a new class of Hoveyda-Grubbs-type catalysts, comprising an N→Ru coordinate bond in a six-membered ring, results in the difficult-to-obtain natural product-like cyclopenta[]furo[2,3-]pyrroles. In this process, only one diastereomer with a -arrangement of the 3-allyl fragment relative to the 3a,6-epoxy bridge enters into the rearrangement, while the -isomers polymerize almost completely under the same conditions. The tested catalysts are active in the temperature range from 60 to 120 °C at a concentration of 0.

[SUBUNITS OF MAMMAL DNA DEPENDENT RNA POLYMERASE III MODIFIED IN VIVO].

In subfractions of DNA-dependent RNA polymerase isolated from nuclei of 3T3 mouse fibroblasts, A431 epidermoid carcinoma cells and mature human placenta, we have identified three subunits modified by both phosphorylation and O-N-acetylglucosamine glucosilation. The subfractions of the human enzyme contained modified subunits with molecular weight of 60 and 45 kDa and a subunit of 52 kDa probably belonging to one of the basal factors of RNA Polymerase III transcription. The subfractions of 3T3 mouse cells RNA Polymerase III consisted of modificated subunits with molecular weight 49, 45 and 42 kDa, however, the 45 kDa subunit might be a component of the basal transcription factor of RNA Polymerase III, since it was not identified in mouse enzyme composition.