Publications by authors named "N A Melek"

Pollen is responsible for seasonal allergies, such as allergic rhino-conjunctivitis (AR), and has become a growing public health concern. Climate change affects the range of allergenic species as well as the timing and length of the pollen season. In Egypt, data on pollinosis are scarce.

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Many metrics such as accuracy rate (ACC), area under curve (AUC), Jaccard index (JI), and Cohen's kappa coefficient are available to measure the success of the system in pattern recognition and machine/deep learning systems. However, the superiority of one system to one other cannot be determined based on the mentioned metrics. This is because such a system can be successful using one metric, but not the other ones.

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Article Synopsis
  • Chronic spontaneous urticaria (CSU) is a common skin condition affecting many people, with around 90% of cases being idiopathic, and nearly half thought to involve autoimmune mechanisms.
  • The study examined the presence of specific T regulatory cells (CD4+CD25highFOXP3+) in CSU patients and their link to autologous serum skin tests (ASST).
  • Results showed that CSU patients had lower levels of these T regulatory cells compared to healthy individuals, supporting the idea that CSU is related to immune system issues and suggesting potential avenues for new treatments.
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Introduction: IgA deficiency is one of the commonest primary antibody deficiencies. Although many affected individuals could be asymptomatic, selected patients suffer from recurrent mucosal infections, allergies, and autoimmune diseases.

Aim Of The Study: To investigate the prevalence of IgA deficiency among Egyptian patients with food allergy.

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Background: The pathogenesis of chronic urticaria is incompletely understood. There is growing interest in the role of the coagulation cascade in chronic urticaria. We aimed to assess the possible activation of the coagulation cascade in chronic spontaneous urticaria (CSU) in relation to disease severity and activity.

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