Publications by authors named "N A M Barakat"

Article Synopsis
  • * Using a novel reactor design, researchers created smooth, stable nanofibers from cobalt acetate and poly(vinyl alcohol) that have a band gap energy of 2.29 eV, allowing strong absorption in the visible spectrum.
  • * The cobalt-based nanofibers demonstrated better hydrogen generation rates compared to traditional CoO nanofibers, achieving 3.266 mmol g s in optimal conditions, and showed good stability over multiple cycles, indicating a promising advance in sustainable energy technology.
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Aim: The current investigations aimed to investigate the potential synergistic effect of Roflumilast (ROF) and Selenium nanoparticles (SeNPs) administration on Cisplatin (Cis) -induced nephrotoxicity.

Materials And Methods: Fifty male rats were divided into five groups; Control group: animals were administered 0.9 % saline solution.

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A novel nickel-molybdenum carbide-graphite nanofiber composite is introduced as an electrocatalyst for ethanol electrooxidation. The proposed nanofibers have been prepared by calcinating electrospun nanofibers composed of nickel acetate tetrahydrate, molybdenum chloride, and polyvinyl alcohol. The calcination process was conducted at different temperatures (700, 850, and 1000°C) under a nitrogen gas atmosphere with a heating rate of 2.

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Article Synopsis
  • The study investigates the link between amyloid-β (Aβ) and cognitive decline in Alzheimer's disease (AD) by analyzing how Aβ affects cortical neuronal function and promotes cellular aging.
  • Researchers used human-derived cortical neurons to measure long-term potentiation (LTP) and found that Aβ reduced LTP and increased senescence, along with the release of inflammatory factors associated with AD.
  • The findings suggest a novel model for understanding AD pathology, indicating that while therapeutic molecules can improve neuronal function, they do not stop Aβ-induced aging, highlighting the need for better treatments.
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A green and sensitive factorial design-assisted reversed-phase high-performance liquid chromatography (RP-HPLC) approach with fluorimetric detection has been developed for simultaneous determination of cinnarizine and domperidone in pure materials, commercial single and combined tablets. Both drugs are co-formulated in one dosage form and are commonly used for the effective treatment of motion sickness in the ratio of 4 : 3 for cinnarizine and domperidone, respectively. To achieve the developed method's best performance and reliability, a 2 full factorial design was applied during the optimization of chromatographic conditions.

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