Publications by authors named "N A Lukash"

Kept under medical surveillance were 120 patients with duodenal ulcer running an uncomplicated course. All patients and 30 healthy donors were studied for the status of the immunity T-system by spontaneous E-rosette formation (E-RFC) and availability of theophylline-resistant (TPP-RFC) and theophylline-sensitive (TPS-RFC) lymphocytes. With B-system being studied by FAC-rosette formation.

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Overall fifty patients with chronic hepatitis and 50 patients with concurrent pathologies were examined. The patients with chronic active hepatitis and in coexisting pathologies showed more profound depression of the immunity system as well as striking alterations on the iris of the eye. The former patient group received basic therapy, while the latter one were given immunomodulating agents against the background of basic therapy.

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A peptide was obtained at our chair, from the mucous membrane of the stomach of the pig, using a method of acid extraction. The above peptide belongs to the group of cytomedines and is conventionally called "mucozaline". As many as 80 Wistar male rats were used in comparative evaluation of thymaline, dallargine and "mucozaline" for their effect on the course of duodenal ulcer in the rat.

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Immunologic concept of pathogenesis of certain diseases wins ever growing number of its proponents. Lack of published data on the state of the immunity system in concurrent pathologies involving biliary and urinary tracts has prompted us to set to study this problem. Studies conducted in 57 patients showed that this condition presents with marked changes in the immune system manifested by activation of humoral immunity at the background of strikingly high degrees of T-cell deficiency.

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120 patients with chronic gastritis and primary chronic gastroduodenitis were given a three-week course of etiopathogenetic treatment (antichelibacterial and immunocorrective drugs) that allowed to diminish the clinical, bacteriological and immune manifestations of the disease and achieve a complete cure in most patients. Patients with marked chelibacteriosis revealed greater refractoriness. The authors recommend prolonged courses of treatment with alternations of etiologically directed drugs.

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