[Quantitative ultrastructural characteristics of the myocardial mitochondria of hypokinetic rats].

Experiments on rats under 30-day hypokinesia have shown an increase in the mitochondrial area in perinuclear, myofibrillar and subsarcolemmal zones of the cardiomyocyte pericaryon, accompanied by a concurrent rise in the number of crests. The crest density index and the amount of mitochondria in te pericaryon diminish. These changes are considered as compensatory-adaptive reconstitution of hypertrophic nature in response to partial destruction of mitochondria.

[Effect of embryonal organ-specific RNA on myocardial hypertrophy].

The relative weight of the heart and the thickness of muscular fibers in the left ventricular myocardium of rats were evaluated 70-91 and 120-227 days after creating stenosis of the abdominal portion of the aorta. Half of the animals were inoculated with cardiac type-specific embryonal RNA, the rest of the animals being intact. The data were treated by the variational statistical technique, by dispersion and mathematic analyses.