[The role of altered respiratory mechanics and systemic inflammation in the development of dyspnea in patients with chronic obstructive pulmonary disease].

Evaluation of the state of respiratory muscles during lung hyperinflation and their role in the development of dyspnea in severe chronic obstructive pulmonary disease involved 18 patients with stage III-IV disease (mean age 66.1 +/- 6.5 yr; mean duration of the disease 16.

[Types of structural-functional disorders in severe chronic obstructive pulmonary disease].

To differentiate approaches to assessment of treatment and prognosis specificities in a severe course of chronic obstructive pulmonary diseases (COPD), a study was made of 30 patients with long-term COPD. The patients were divided into groups by the severity of respiratory insufficiency which was investigated by saturation of 0(2) and gas composition of arterialized capillary blood, flow-volume curve and bodyplethysmography, ECG, echo-CG. High resolution computed tomography of the lungs was used to evaluate diffuse changes of pulmonary tissue and its morphological rearrangement.