[Prenatal and postnatal prevention of iodine deficiency in the first year of life].

A total of 260 females were studied in an iodine-deficient regions in different periods of gestation. Among them, 123 females were examined during pregnancy and within 3 months of lactation. Iodine deficiency during pregnancy was shown to form a high risk for diseases in both a child and a mother.

[Prevalence of somatic diseases in children with endemic goiter].

A total of 1649 children aged 0 to 16 years were examined in the Khvalynsk district of the Saratov region endemic for goiter. Age-specific features of prevalence of goiter and chronic somatic diseases were studied. Goiter was found to form starting from the first years of life, with its morbidity peaks observed at the age of 3, 5, 7, and 12.

[Characteristics of sexual maturation of girls with juvenile hyperplasia of the thyroid gland].

Overall 69 girls with stage II and III juvenile hyperplasia of the thyroid without any clinical signs of pubertal abnormality were examined. Of these, 2/3 had the normal content of circulating thyroid and thyrotropic hormones in the blood serum. In prepubertal girls, the age-associated basal concentrations of gonadotropins and sexual steroid were discovered, whereas in puberty, there was a significant increase of the content of luteinizing hormone, prolactin, estradiol (a two-fold increase) and progesterone (a ten-fold increase) in the second phase of the menstrual cycle, which attested to its ovulatory nature.