[Psychoemotional and autonomic states in patients with cholelithiasis].

Aim: To investigate the psychoemotional and autonomic states of patients with biliary system diseases and to determine their significance in the development of cholelithiasis.

Subjects And Methods: A total of 396 patients with stage 1 cholelithiasis were examined. The results of hepatobiliary ultrasonography, multifractional duodenal probing, followed by macroscopic, microscopic, and biochemical examinations of bile (the total concentration of bile acids and cholesterol, by subsequently calculating the cholate-cholesterol ratio) were used to verify the diagnosis.

[Cholelithiasis as a possible manifestation of systemic digestive diseases].

Aim: To comprehensively study of the function of digestive organs in cholelithiasis (CL).

Subjects And Methods: Three hundred and seventeen patients with the early (prestone) stage of CL were examined. The latter was verified by ultrasonography (USG) and biochemical bile tests.

[Wether cholescystectomy affects bile lithogenicity in cholelithiasis].

The Aim: The studying of physical-chemical qualities of liver bile and lipid exchange before and after cholecystectomy.

Materials And Methods: We spent the complex investigation of physical-chemical qualities of bile and lipid levels in 210 patients with cholelithiasis stage I (pre-stone) and in 90 patients with cholelithiasis stage II and III (with gallstones) after cholecystectomy.

The Results: In all examined patients we revealed disturbances of physical-chemical qualities of bile and lipid exchange.

[Ways to improve efficiency of patient clinical examinations during early stage of cholelithiasis].

Purpose: The aim of the work was to improve the organization and conduct of clinical examination of patients with gallstone disease (GSD).

Materials And Methods: An integrated study of 396 patients with different pathologies of the hepatobiliary system and the medical check-up for three years for 101 patients.

Results: Built logistic model to predict the likelihood of developing gallstone disease and developed a predictive scoring table it possible to distinguish patients at risk of developing gall stones.

[Possibilities of using of crystal-optic qualities of bile in early diagnostic stage of cholelithiasis].

The aim of our investigation was to study the changes of bile morphology and possibilities of its using in early diagnostic stage of cholelithiasis. We spent the complex investigation of biochemical and crystal-optic qualities of bile in 207 patients with cholelithiasis stage I with different disease duration. The revealed crystal-optic morphotypes have selective morphology due to the bile lithogene level that allows to determine the disease duration and the bile instability to make in-time adequate profilactic.