[Humoral and cellular immunity in meningitis of various etiology].

The parameters of humoral and cellular immunity were studied in patients with meningitis due to tuberculosis and other diseases. Peripheral blood and spinal fluid were measured in 91 and 76 patients with tuberculous meningitis, in 75 and 59 with purulent meningitis, and in 54 and 33 with serous meningitis, respectively. Comparing assessment of the findings revealed profound changes in the content of T lymphocytes and their subpopulations.

[Distribution of transplantation HLA antigens in children and adolescents with meningitis of various etiology].

An interaction between HLA antigens and predisposition to meningitis of specific and nonspecific etiology was studied in children and adolescents from an Azerbaijan population. The distribution of HLA antigens was found to be heterogeneous in the patients with meningitis of various etiology. Tuberculous meningitis was characterized by a significant rise in the detection rate of HLA-DR3 antigen, by a considerable frequency of B14 and DR2 antigens; patients with purulent meningitis much more significantly showed HLA-B12 antigen; in terms of locus A, there was an increase in the detection rates of HLA-A19 antigen in serous meningitis.

[Comparative analysis of the results of spinal fluid microbiological study in children and adults who suffered from tuberculous meningitis].

An examination was made of 133 children and 89 adults, aged 3 to 60 years, who had admitted for suspected tuberculous meningitis. The diagnosis of tuberculous meningitis was established in 113 children and 79 adults. In the remaining 20 ill children and 10 adult patients, tuberculous etiology of the disease was rejected.