Experiments were performed to address the dynamics of evoked focal potentials in slices of rat olfactory cortex during 10-min anoxia and subsequent reoxygenation. These experiments showed that perfusion with corticotropin-releasing factor (CRF)--corticoliberin--at concentrations of 1, 10, and 100 nM had no effect on changes in EPSP parameters before or during anoxia. However, CRF (10 and 100 nM) significantly aided recovery of the amplitude and slope of EPSP during reoxygenation.
View Article and Find Full Text PDFExperiments were performed to investigate evoked focal potentials in slices of rat olfactory cortex. The results showed that 1 microM corticotropin-releasing factor (CRF; corticoliberin) increases the frequency of posttetanic potentiation, which had a shorter delay phase than in control experiments. Posttetanic potentiation during perfusion with 0.
View Article and Find Full Text PDFDecreased binding capacity of corticosteroid-binding protein in rats subjected to prolonged immobilization stress is related to reduction in the contents of triiodothyronine and thyroxin, rather than to a continuous increase in blood corticosterone concentration.
View Article and Find Full Text PDFNeurosci Behav Physiol
February 1999
Existing data on the role of Ca2+ ions in the development of long-term potentiation were used as a basis for studying changes in different Ca2+ compartments in cells in living rat olfactory cortex slices during potentiation. The kinetics of 45Ca2+ exchange were studied at 5, 15, and 30 min of potentiation. During the induction phase (1-5 min) of long-term potentiation, the fraction of tightly-bound intracellular Ca2+ decreased.
View Article and Find Full Text PDFLong-term potentiation was elicited in living slices of rat olfactory cortex by stimulation of the lateral olfactory tract. A group of interdependent parameters of membrane metabolism was studied, i.e.
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