Publications by authors named "N A Didkovskii"
Background/aim: In chronic spontaneous urticaria (CSU), Helicobacter pylori (HP) has been discussed as a cause, but it is unknown whether the bacterium itself or concomitant inflammation is causing the urticaria. Our aim was to investigate HP and upper gastrointestinal lesions as signs of inflammation independently of each other in the pathogenesis of CSU.
Methods: A total of 36 prospectively enrolled CSU patients from Moscow were investigated by gastroscopy and screened for the presence of HP and/or upper gastrointestinal lesions.
Aim: To study neutrophil bacterial and absorptive functions and the specific features of their impairments in gout.
Subjects And Methods: The study included 48 male patients with a valid diagnosis of gout (mean age, 59.7 +/- 10.
We studied the state of antiviral defense in patients with severe course of herpetic infection of anogenital and labial localization and the frequency of its combination with other herpes virus infections. It was found that severe course of herpetic infection caused by herpes simplex virus occurs against the background of combined secondary immunodeficiency and its complication. We first demonstrated that severe course of the disease is associated with mixed viral infection.
View Article and Find Full Text PDFAim: To study antiviral defense in patients with severe anogenital and labial herpetic infection, prevalence of herpetic infection and possible combination with other strains.
Material And Methods: The immune status (basic lymphocyte subpopulations, IgA, IgM, IgG, circulating immune complexes in blood serum, cytokines, interferon status, functional activity of neutrophils) was investigated in 102 patients with severe Herpex simplex infection (HSI).
Results: Marked deficiency and hyporeactivity of natural and/or specific cytotoxicity were found in 70% HSI patients with severe disease.