[Characteristics of circadian variability of heart rate during Holter monitoring].

24-hour Holter monitoring of 60 healthy children aged 3 to 15 years provided criteria for assessing the circadian heart rate (HR) variations as a measure of alterations occurred in autonomic heart rhythm control. Specific HR dynamics during their sleep is described, which involves changes in steady-state rhythm and higher dispersion periods associated with the alternation of slow and fast sleep phases. Sex- and age-related HR features are defined during 24-hour monitoring.

[Changes in central hemodynamics as a risk factor of the development of ischemic heart disease in adolescents with aggravated heredity of atherosclerosis].

The authors provide the data on the central hemodynamics, blood plasma lipoproteins and apoproteins in 101 adolescents with aggravated heredity as regards coronary heart disease and in healthy adolescents of the same age serving as control. The hypokinetic variant of circulation is demonstrated to be coupled with the atherogenic nature of the lipoprotein and apoprotein spectra and heredity to contribute greatly to the traits under study. Criteria for the adolescents' inclusion into the group at the highest risk for early development of atherosclerosis are described.

[The role of genetic and environmental factors in phenotypic variability of arterial pressure and body weight and their interconnection (a family study)].

Contribution of genetic and environmental factors into phenotypic variability of blood pressure and body mass as well as into phenotypic correlation between these traits was defined. It was shown that additive genetic determinant is responsible for considerable level of blood pressure and body mass variability. Those common environmental factors are of importance which operate within the limits of one generation.