Publications by authors named "N A Barnes"
Background: The opioid epidemic has severely impacted the US over the last 15 years. Buprenorphine is a partial opioid agonist indicated for the treatment of opioid use disorder (OUD) and is recognized as an effective treatment when taken as prescribed. However, adherence rates have been low in real-world settings.
View Article and Find Full Text PDFIntroduction: There is a paucity of research on and a limited understanding of patient and public involvement (PPI) in the context of research in homelessness and, in particular, direct involvement of people with lived and living experience of homelessness (PEH) as expert advisors. We aim to report on outcomes and reflections from lived experience advisory panel (LEAP) meetings and PPI activities, held throughout the study lifecycle of a pilot randomised-controlled trial (RCT) focused on evaluating integrated health and practical support for PEH.
Methods: Community Pharmacy Homeless Outreach Engagement Non-medical Independent prescribing Rx (PHOENIx Community Pharmacy RCT) is an integrated health and social care intervention for people experiencing homelessness who present to community pharmacy.
Purpose: To model the potential clinical and economic impact of blister-packaging medications for chronic conditions on medication adherence and healthcare costs in a commercially insured population.
Methods: A health economic model was developed to evaluate the potential impact of blister-packaging chronic medications for a commercially insured population. The chronic medication classes assessed were renin-angiotensin-system (RAS) antagonists, statins, non-insulin oral antidiabetics, and direct oral anticoagulants (DOACs).
Article Synopsis
- Mental health issues among healthcare professionals in ICUs are serious, with burnout rates reaching up to 50%, and factors affecting burnout include communication and support systems.
- The 'Hello Bundle' intervention was created to combat burnout by enhancing social interactions and team cohesion, using elements like posters, email reminders, and daily greetings.
- A cluster randomized controlled trial will assess the effectiveness of the 'Hello Bundle', involving around 7,300 participants from various ICUs, comparing burnout levels before and after the intervention.
Purpose: To assess the feasibility of a second-generation (44-channel) suprachoroidal retinal prosthesis for provision of functional vision in recipients with end-stage retinitis pigmentosa (RP) over 2.7 years.
Design: Prospective, single-arm, unmasked interventional clinical trial.