Publications by authors named "N A B Simpson"

High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

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Objective: Type 2 diabetes (T2D) now accounts for the majority of pre-existing diabetes affecting pregnancy in the UK. Our aim was to determine its impact on pregnancy outcomes compared to type 1 diabetes (T1D), gestational diabetes (GDM), and nondiabetes pregnancies.

Data Sources: PubMed was searched 1 January 2009 to 2024.

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Objective: This study aimed to increase understanding of the signs and symptoms that lead pregnant people to seek hospital care in the second trimester of pregnancy. In addition, we aimed to describe management and follow up, to record pregnancy outcomes, and to gather information about symptoms and signs related to second trimester pregnancy loss.

Methods: This prospective audit in seven geographically dispersed sites across the UK collected data over two weeks (7th March-20th March 2022 inclusive) on all unscheduled secondary care attendances between 14 and 21 completed weeks' gestation.

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Article Synopsis
  • Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are commonly used in treating heart failure (HF), but their association with ketosis risk during hospitalization is uncertain.
  • A study measured ketone levels in hospitalized patients with worsening HF and stable HF to determine if SGLT2i use influenced ketone concentrations.
  • Results showed that ketone levels were low across all patients, regardless of SGLT2i use or the severity of heart failure, indicating minimal risk of ketosis in these individuals.
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  • The study investigates the safety and feasibility of paramedics administering buprenorphine to treat opioid withdrawal in the field without needing online medical control.
  • A review of 121 cases showed that no adverse effects from the medication were reported, although some patients experienced nausea and vomiting, which were already present before treatment.
  • The findings suggest that using buprenorphine prehospital is a viable option for addressing acute opioid withdrawal in patients.
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