Publications by authors named "N A Anuar"

This study aims to evaluate the impact of formulation parameters on tannic acid-crosslinked gelatine (GelTA) films, intended as a mucoadhesive matrix for extended buccal drug delivery. GelTA films were prepared using the solvent evaporation technique and screened based on their mucoadhesive and dissolution characteristics. The formulation variables included the source of gelatine (bovine and fish), tannic acid concentration, pH of the film-forming solutions, and the type and concentration of plasticisers.

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Article Synopsis
  • Heterotopic pancreas is a rare condition often misdiagnosed before surgery, commonly found in the upper gastrointestinal tract, but can also occur in unusual locations such as the thorax and kidneys.
  • A case study highlighted a patient with intermittent abdominal pain and weight loss, leading to the discovery of a heterotopic pancreas during surgery after imaging indicated a suspicious growth in the duodenum.
  • Challenges in diagnosis include the lesion's site and characteristics; while biopsies can help, they are often non-diagnostic, and the only definitive treatment is surgical resection.
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Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction and communication, as well as the occurrence of stereotyped and repetitive behaviors. Previous studies have provided solid evidence of dysregulated immune system in ASD; however, limited studies have investigated autoantibody profiles in individuals with ASD. This study aims to screen plasma autoantibodies in a well-defined cohort of young children with ASD (n = 100) and their matched controls (n = 60) utilizing a high-throughput KoRectly Expressed (KREX) i-Ome protein-array technology.

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Article Synopsis
  • * There is a strong necessity for effective antifungal treatments due to the severity of some Candida infections, leading to the development of controlled drug delivery strategies aiming for better release and targeting of antifungal agents.
  • * The article reviews how bioadhesive polymers can improve drug delivery systems for antifungal medications, promoting sustained release and reducing dosing frequency while also evaluating the effectiveness and mechanisms of these systems in treating candidiasis.
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