Not one size fits all: a half-mask-based GKRS treatment for preservation of a scalp flap. Illustrative case.

Background: Implementing the thermoplastic mask as a treatment option in Gamma Knife radiosurgery (GKRS) has madethe discussion of the relative benefits of frame- or mask-based fixation for treatment a frequent occurence. Based on a case review, the authors discuss factors that need to be understood and considered by the treating team.

Observations: The authors describe the case of an 81-year-old patient with pleomorphic dermal sarcoma that extended to and infiltrated the dura mater, who underwent extensive resection requiring a skin flap.

Pregnant women with periodontal disease: can complete blood count be useful?

Prenatal care is of fundamental importance and must be carried out by a multidisciplinary healthcare team, including dental care, as several changes and complications affecting the oral cavity may occur during pregnancy. This was a cross-sectional study that aimed to analyze the hematological profile of pregnant women with and without periodontal disease (PD). Data were obtained by consulting medical and dental records, which were stratified into two subgroups: pregnant women with PD (n=107) and pregnant women without PD (n=42).

Metabolomic analysis to study the effect of foliar copper supplementation on sulfur-containing compounds of garlic bulb by LC-MS.

Introduction: Garlic (Allium sativum L.) is renowned for its health-promoting properties, largely due to its sulfur-rich compounds. While copper is essential for plant growth and metabolism, excessive levels can disrupt cellular processes and lead to oxidative stress.

Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors.

We here describe the design, synthesis, and biological activity of novel ornithine decarboxylase (ODC) inhibitors that show significantly higher potency than α-difluoromethylornithine (DFMO), a U.S. Food and Drug Administration (FDA) approved drug.