An mHealth App (eSkinHealth) for Detecting and Managing Skin Diseases in Resource-Limited Settings: Mixed Methods Pilot Study.

Background: In sub-Saharan Africa, the disease burden from skin diseases, including skin-related neglected tropical diseases (skin NTDs), is extremely high. These diseases often are overlooked due to limited access to health care stemming from, for example, remote geographical locations and a lack of experts. To address these gaps, we developed a mobile health app, eSkinHealth, which is a field-adapted platform to serve as a portable electronic patient chart and for teledermatology.

[Contribution of the AVR lead in the diagnosis of ischemic heart disease in one case at the Institute of Cardiology of Abidjan (Ivory Coast)].

Abnormalities in the aVR lead would provide useful information on the risk of coronary heart disease. This clinical case is an illustration. Indeed, this is a 60-year-old patient, an active smoker and a former type 2 diabetic who presented with angina-like chest pain with a positive stress test.

[Levine's sign in the diagnosis of acute coronary syndrome with non-contributory electrocardiogram: About one case at the Abidjan Cardiology Institute (Ivory Coast)].

Acute chest pain is usually expressed in typical language; which is sometimes assigned a particular sign. One of the signs is that of Levine, usuallytranslating a coronary involvement. This clinical case highlights a patient who is admitted for chest pain with Levine's sign and a non-contributory electrocardiogram.

Emergence in Western African countries of MDR-TB, focus on Côte d'Ivoire.

Tuberculosis (TB) is responsible for a high mortality rate (2.5%) worldwide, mainly in developing countries with a high prevalence of human immunodeficiency virus (HIV). The emergence of multiresistant strains of TB poses an extreme risk for TB outbreaks and highlights the need for global TB control strategies.

Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring.

Background: Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis and disease monitoring. Whether mycolactone diffuses from ulcerated lesions in clinically accessible samples and is modulated by antibiotic therapy remained to be established.

Methodology/principal Finding: Peripheral blood and ulcer exudates were sampled from patients at various stages of antibiotic therapy in Ghana and Ivory Coast.

Multilocus VNTR analysis of Mycobacterium ulcerans strains isolated in Côte d'Ivoire.

Introduction: Buruli ulcer, caused by Mycobacterium ulcerans, is endemic in more than 30 countries worldwide, with Côte d'Ivoire being among the most affected countries.

Methodology: We used seven variable number of tandem repeats (VNTR) markers and analyzed 114 samples from 11 Ivorian localities consisting of 33 bacterial strains and 81 clinical samples. Complete data sets at loci 1, 6, 9 and 33 were obtained for 18 of these strains (n = 15) and samples (n = 3) collected in each of the localities.