Assessment of the burden of malaria and bacteraemia by retrospective molecular diagnosis in febrile illnesses and first-line anti-infectives in Côte d'Ivoire.

Background: The aetiologies of fever are poorly understood in sub-Saharan Africa. We aimed to assess the burden of malaria and bacteria in Côte d'Ivoire.

Methods: Blood samples from 438 febrile and 346 afebrile people were screened using molecular tools.

Multiple Pathogens Including Potential New Species in Tick Vectors in Côte d'Ivoire.

Background: Our study aimed to assess the presence of different pathogens in ticks collected in two regions in Côte d'Ivoire.

Methodology/principal Findings: Real-time PCR and standard PCR assays coupled to sequencing were used. Three hundred and seventy eight (378) ticks (170 Amblyomma variegatum, 161 Rhipicepalus microplus, 3 Rhipicephalus senegalensis, 27 Hyalomma truncatum, 16 Hyalomma marginatum rufipes, and 1 Hyalomma impressum) were identified and analyzed.

Hepatoprotective and in vivo antioxidant activity of Olax subscorpioidea Oliv. (Olacaceae) and Distemonathus benthamianus Baill. (Caesalpiniaceae).

Background: Liver diseases are on rise and remain a serious health problem. Olax subscorpioidea and Distemonanthus benthamianus are two plants used in Ivorian traditional medicine in the treatment of many diseases including jaundice and hepatitis.

Objective: The present study was carried out to assess the hepatoprotective and in vivo antioxidant potentials of the hydro-ethanolic leaf extracts of these plants in carbon tetrachloride (CCl4)-induced hepatotoxicity in rats.

[Evaluation of the anti-inflammatory activity and phytochemical screening of Annona senegalensis leaves].

Objective: This study aims to highlight the anti-inflammatory activity of ethanol extract of Annona senegalensis and do its phytochemical screening.

Methods: Rats were divided into three groups. The first group received only saline injection and instillation by intraperitoneal injection on days D0 and D7.

Bio-guided isolation of antioxidant compounds from Chrysophyllum perpulchrum, a plant used in the Ivory Coast pharmacopeia.

Chrysophyllum perpulchrum (Sapotaceae) is used in the traditional Ivory Coast pharmacopeia to cure fevers. The extract of C. perpulchrum used for this study was the powdered form obtained from the maceration of the dried plant bark in 96% methanol, followed by evaporation to dryness.

Influence of Mitragyna ciliata (MYTA) on the microsomal activity of ATPase Na+/K+ dependent extract on a rabbit heart.

Mitragyna ciliata (MYTA) (Rubiaceae) inhibits plasmodia activity. MYTA induces a cardiotonicity of the digitalic type on rat's isolated heart. In this work we studied the effect of MYTA on microsomal Na(+)/K(+) dependant ATPase (Na(+), K(+) ATPase) extracted from the heart of a rabbit since digitalics inhibit Na(+), K(+) ATPase.