Characterization of Gold-Enhanced Titania: Boosting Cell Proliferation and Combating Bacterial Infestation.

Background: In this study an approach was made to efficaciously synthesize gold enhanced titania nanorods by electrospinning. This study aims to address effects of gold enhanced titania nanorods on muscle precursor cells. Additionally, implant related microbial infections are prime cause of various disastrous diseases.

Biocompatibility Computation of Muscle Cells on Polyhedral Oligomeric Silsesquioxane-Grafted Polyurethane Nanomatrix.

This study was performed to appraise the biocompatibility of polyhedral oligomeric silsesquioxane (POSS)-grafted polyurethane (PU) nanocomposites as potential materials for muscle tissue renewal. POSS nanoparticles demonstrate effectual nucleation and cause noteworthy enhancement in mechanical and thermal steadiness as well as biocompatibility of resultant composites. Electrospun, well-aligned, POSS-grafted PU nanofibers were prepared.

Oxalic acid assisted rapid synthesis of mesoporous NiCoO nanorods as electrode materials with higher energy density and cycle stability for high-performance asymmetric hybrid supercapacitor applications.

In this study, mesoporous nickel cobaltite (NiCoO) nanorods as electrode materials for high-performance hybrid supercapacitor were fabricated onto Ni foam by a simple and cost effective oxalic acid (OA) assisted rapid co-precipitation method. The effects of different metal precursors (NCO-Nitrate, NCO-Chloride and NCO-Acetate) on the electrochemical capacitive properties were studied. FE-SEM analysis confirmed that all samples exhibited highly dense mesoporous NiCoO nanorods vertically grown on the surface of Ni foam with excess accessible surfaces and unique sizes and morphologies.

Preparation and evaluation of β-glucan hydrogel prepared by the radiation technique for drug carrier applications.

β-Glucan can provide excellent environment to apply to drug carrier due to its immunological and anti-inflammatory effect. Minocycline hydrochloride (MH) has excellent oral bioavailability pharmacological properties. Specifically, MH is effectively absorbed into the gingiva for periodontal disease treatment.

Electrically and Thermally Conductive Carbon Fibre Fabric Reinforced Polymer Composites Based on Nanocarbons and an In-situ Polymerizable Cyclic Oligoester.

There is growing interest in carbon fibre fabric reinforced polymer (CFRP) composites based on a thermoplastic matrix, which is easy to rapidly produce, repair or recycle. To expand the applications of thermoplastic CFRP composites, we propose a process for fabricating conductive CFRP composites with improved electrical and thermal conductivities using an in-situ polymerizable and thermoplastic cyclic butylene terephthalate oligomer matrix, which can induce good impregnation of carbon fibres and a high dispersion of nanocarbon fillers. Under optimal processing conditions, the surface resistivity below the order of 10 Ω/sq, which can enable electrostatic powder painting application for automotive outer panels, can be induced with a low nanofiller content of 1 wt%.

Encapsulation of β-Sitosterol in Polyurethane by Sol-Gel Electrospinning.

Pristine β-sitosterol or in combination with other phytosterols is utilized in an array of enriched commercial foods. Considering the presence of β-sitosterol in different functional foods and its potential role in prevention and cure of neurodegenerative diseases, the aims of our investigation were to encapsulate β-sitosterol in nanofibers and to estimate influence of β-sitosterol on proliferation of fibroblasts. Electrospun nanofibers have widely been used as scaffolds to mimic natural extracellular matrix.

Imaging, Spectroscopic, Mechanical and Biocompatibility Studies of Electrospun Tecoflex EG 80A Nanofibers and Composites Thereof Containing Multiwalled Carbon Nanotubes.

The present study discusses the design, development and characterization of electrospun Tecoflex EG 80A class of polyurethane nanofibers and the incorporation of multiwalled carbon nanotubes (MWCNTs) to these materials. Scanning electron microscopy results confirmed the presence of polymer nanofibers, which showed a decrease in fiber diameter at 0.5% wt.

Virgin olive oil blended polyurethane micro/nanofibers ornamented with copper oxide nanocrystals for biomedical applications.

Recently, substantial interest has been generated in using electrospun biomimetic nanofibers of hybrids, particularly organic/inorganic, to engineer different tissues. The present work, for the first time, introduced a unique natural and synthetic hybrid micronanofiber wound dressing, composed of virgin olive oil/copper oxide nanocrystals and polyurethane (PU), developed via facile electrospinning. The as-spun organic/inorganic hybrid micronanofibers were characterized by scanning electron microscopy (SEM), energy dispersive X-ray analysis, X-ray diffraction, electron probe microanalysis, and transmission electron microscopy.

Characterization and antimicrobial property of poly(acrylic acid) nanogel containing silver particle prepared by electron beam.

In this study, we developed a one step process to synthesize nanogel containing silver nanoparticles involving electron beam irradiation. Water-soluble silver nitrate powder is dissolved in the distilled water and then poly(acrylic acid) (PAAc) and hexane are put into this silver nitrate solution. These samples are irradiated by an electron beam to make the PAAc nanogels containing silver nanoparticles (Ag/PAAc nanogels).

Apoptosis induced by copper oxide quantum dots in cultured C2C12 cells via caspase 3 and caspase 7: a study on cytotoxicity assessment.

We report herein the synthesis and characterization of copper oxide quantum dots and their cytotoxic impact on mouse C2C12 cells. The utilized CuO quantum dots were prepared by the one-pot wet chemical method using copper acetate and hexamethylenetetramine as precursors. The physicochemical characterization of the synthesized CuO quantum dots was carried out using X-ray diffraction, energy-dispersive X-ray analysis, and transmission electron microscopy.

Fabrication and characterization of II-VI semiconductor nanoparticles decorated electrospun polyacrylonitrile nanofibers.

Semiconductor nanoparticles incorporated highly aligned electrospun polyacrylonitrile (PAN) composite nanofibers were obtained via a simple, scalable and low-cost dip coating technique at room temperature. The resultant PAN nanofibers exhibited good incorporation of CdS, ZnS and CoS semiconductor nanoparticles. The detailed characterizations of these composite nanofibers were investigated.

Electrospun Fe3O4/TiO2 hybrid nanofibers and their in vitro biocompatibility: prospective matrix for satellite cell adhesion and cultivation.

We report the fabrication of novel Fe3O4/TiO2 hybrid nanofibers with the improved cellular response for potential tissue engineering applications. In this study, Fe3O4/TiO2 hybrid nanofibers were prepared by facile sol-gel electrospinning using titanium isopropoxide and iron(III) nitrate nonahydrate as precursors. The obtained electrospun nanofibers were vacuum dried at 80 °C and then calcined at 500 °C.

One-step facile construction of high aspect ratio Fe3O4 decorated CNFs with distinctive porous morphology: potential multiuse expectations.

The objective of our study was to develop a new class of Fe3O4 nanocrystals decorated CNFs with characteristic porous morphology by straightforward approach. The utilized CNFs-Fe3O4 hybrid was prepared by sol-gel electrospinning employing polyacrylonitrile and iron (III) nitrate nonahydrate as precursors. Scanning electron microscopy, energy dispersive X-ray spectroscopy, transmission electron microscopy and X-ray diffraction techniques were employed to characterize novel CNFs-Fe3O4 composite.

Classy non-wovens based on animate L. gasseri-inanimate poly(vinyl alcohol): upstream application in food engineering.

We explored electrospinning as a feasible and practicable mode for encapsulation and stabilization of Lactobacillus gasseri. The utilized nanocomposite was prepared using sol-gel composed of animate L. gasseri and inanimate PVA.

Novel silicificated PVAc/POSS composite nanofibrous mat via facile electrospinning technique: potential scaffold for hard tissue engineering.

This study presents the fabrication of novel porous silicificated PVAc/POSS composite nanofibers by facile electrospinning technique and the interaction of synthesized mats with simulated body fluid (SBF). The physicochemical properties of the electrospun composites were determined by scanning electron microscopy, energy dispersive X-ray spectroscopy, transmission electron microscopy, electron probe micro-analysis, X-ray diffraction and thermogravimetry analysis. To examine the in vitro cytotoxicity, mouse myoblast C2C12 cells were treated with pristine and composite nanofibrous mats and the viability of cells was analyzed by cell counting kit-8 assay at regular time intervals.

TiO2 nanorods via one-step electrospinning technique: a novel nanomatrix for mouse myoblasts adhesion and propagation.

This study was aimed at the synthesis and characterization of novel Titania nanorods by sol-gel electrospinning technique. The physicochemical properties of the synthesized nanorods were determined by field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), and X-ray diffraction (XRD) pattern. To examine the in vitro cytotoxicity, mouse myoblast C2C12 cells were treated with different concentrations of as prepared TiO(2) nanorods and the viability of cells was analyzed by Cell Counting Kit-8 assay at regular time intervals.

Fabrication, characterization and antibacterial effect of novel electrospun TiO2 nanorods on a panel of pathogenic bacteria.

This study is aimed at the synthesis and characterization of novel Titania nanorods by sol-gel electrospinning technique. The physicochemical properties of the synthesized nanorods were determined by FE-SEM, EDX, TEM, TGA and XRD. We investigated the photocatalytic activity of Titania nanorods for degrading Rhodamine 6G dye and discussed the antibacterial activity and interaction mechanism against four pathogenic bacteria viz.

Preparation, characterization, and cytotoxicity of CPT/Fe₂O₃-embedded PLGA ultrafine composite fibers: a synergistic approach to develop promising anticancer material.

The aim of this study was to fabricate camptothecin/iron(III) oxide (CPT/Fe₂O₃)-loaded poly(D,L-lactide-co-glycolide) (PLGA) composite mats to modulate the CPT release and to improve the structural integrity and antitumor activity of the released drug. The CPT/Fe₂O₃-loaded PLGA ultrafine fibers were prepared for the first time by electrospinning a composite solution of CPT/Fe₂O₃ and neat PLGA (4 weight percent). The physicochemical characterization of the electrospun composite mat was carried out by scanning electron microscopy, energy dispersive X-ray spectroscopy, electron probe microanalysis, thermogravimetry, transmission electron microscopy, ultraviolet-visible spectroscopy, and X-ray diffraction pattern.

Smart copper oxide nanocrystals: synthesis, characterization, electrochemical and potent antibacterial activity.

We report herein the synthesis and characterization of novel CuO nanocrystals and their electrochemical and potent antibacterial activity. The utilized CuO nanocrystals were prepared by wet chemical method using copper acetate and hexamethylenetetramine (HMTA) as precursors. The physicochemical properties of the synthesized CuO nanocrystals having size ~6 nm were determined by X-ray diffractometer (XRD), energy dispersive X-ray analysis (EDX), transmission electron microscopy (TEM) and ultra violet-visible (UV-Vis) spectroscopy.

Controlled synthesis of Mn₂O₃ nanowires by hydrothermal method and their bactericidal and cytotoxic impact: a promising future material.

Mn₂O₃ nanowires with diameter ~70 nm were synthesized by a simple hydrothermal method using Mn(II) nitrate as precursor. X-ray diffraction, field emission scanning electron microscopy, transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy techniques were employed to study structural features and chemical composition of the synthesized nanowires. A biological evaluation of the antimicrobial activity and cytotoxicity of Mn₂O₃ nanowires was carried out using Escherichia coli and mouse myoblast C₂C₁₂ cells as model organism and cell lines, respectively.

Antibacterial activity and interaction mechanism of electrospun zinc-doped titania nanofibers.

In this study, a biological evaluation of the antimicrobial activity of Zn-doped titania nanofibers was carried out using Escherichia coli ATCC 52922 (Gram negative) and Staphylococcus aureus ATCC 29231 (Gram positive) as model organisms. The utilized Zn-doped titania nanofibers were prepared by the electrospinning of a sol-gel composed of zinc nitrate, titanium isopropoxide, and polyvinyl acetate; the obtained electrospun nanofibers were vacuum dried at 80°C and then calcined at 600°C. The physicochemical properties of the synthesized nanofibers were determined by X-ray diffraction pattern, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, electron probe microanalysis, thermogravimetry, and transmission electron microscopy (TEM).

In-vitro cytotoxicity and cell uptake study of gelatin-coated magnetic iron oxide nanoparticles.

The aim of this study was to modify the surfaces of magnetic iron oxide nanoparticles (IOPs) with gelatin in order to reduce cytotoxicity and enhance cellular uptake. The gelatin-coated IOPs were characterized in terms of their functionalization, size, surface charge, morphology and crystalline structure using Fourier transform infrared (FT-IR) spectroscopy, thermogravimetric analysis (TGA), dynamic light scattering (DLS), transmission electron microscopy (BIO-TEM) and x-ray diffraction (XRD) analysis. The cytotoxicity of the gelatin-coated IOPs to human fibroblasts was assessed using an MTT-assay and was compared with uncoated IOPs.

Synchronized polymerization and fabrication of poly(acrylic acid) and nylon hybrid mats in electrospinning.

Acrylic acid monomer in a viscous supporting nylon solution was polymerized and fabricated simultaneously via an electrospinning process. This novel polymerization method defines the fiber morphology as a network of interconnected mats. This network consists of smaller poly(acrylic acid) (PAA) fibers, approximately 19 nm in diameter, and larger nylon 6 fibers, approximately 75 nm in diameter.

Novel self-assembled amphiphilic poly(epsilon-caprolactone)-grafted-poly(vinyl alcohol) nanoparticles: hydrophobic and hydrophilic drugs carrier nanoparticles.

In the present study, we have aimed to produce nanoparticles (NPs) possessing the capability of carrying both of the hydrophobic and hydrophilic drugs and reveal significant release for both drug types. Poly(epsilon-caprolactone) (PCL) grafted poly(vinyl alcohol) (PVA) copolymer (PCL-g-PVA) has been prepared and shaped in nano-particulate form to be adequate for carrying the drugs. Stannous octoate (Sn(II)Oct(2)) was used to catalyze PVA and epsilon-caprolactone monomer to chemically bond.

Bioactivity of gelatin coated magnetic iron oxide nanoparticles: in vitro evaluation.

Current research explores formation of bone like apatite on gelatin coated magnetic iron oxide nanoparticles (GIOPs) to evaluate the bioactivity of the material. The GIOPs were soaked in simulated body fluid (SBF) and the apatite formation on the surface was investigated in regular interval of time. Fourier transform-infrared (FT-IR) and x-ray diffraction spectroscopic (XRD) analyses were done to investigate the chemical changes and field emission-scanning electron microscopic (FE-SEM) analysis was done to investigate the morphological changes occurring on the surface of the GIOPs after soaking in different time intervals.