Publications by authors named "Myung A Kim"
Objective: Although several studies have highlighted the benefits of statins in improving arterial stiffness, there is limited research on whether pitavastatin, a more recently developed statin, has similar effects. This study aimed to investigate the impact of pitavastatin on arterial stiffness in patients with hypercholesterolemia.
Methods: This prospective study enrolled 115 patients with hypercholesterolemia (mean age, 59 years; 22% female) who had not previously been treated with statins.
Article Synopsis
- The study examined how socioeconomic status (SES), including income and education, affects arterial stiffness as measured by estimated pulse wave velocity (ePWV) among 13,539 participants in South Korea.
- Results showed that while personal income had no significant impact on ePWV, higher household income and higher education levels were linked to lower ePWV values.
- The findings suggest that individuals with lower income and education levels experience greater arterial stiffness, highlighting the importance of SES in cardiovascular health.
Intravascular imaging-guided percutaneous coronary intervention in patients with acute myocardial infarction and cardiogenic shock.
Rev Esp Cardiol (Engl Ed)
December 2024
Introduction And Objectives: There are no clinical data on the efficacy of intravascular imaging-guided percutaneous coronary intervention (PCI) compared with angiography-guided PCI in patients with acute myocardial infarction (AMI) and cardiogenic shock. The current study sought to evaluate the impact of intravascular imaging-guided PCI in patients with AMI and cardiogenic shock.
Methods: Among a total of 28 732 patients from the nationwide pooled registry of KAMIR-NIH (November, 2011 to December, 2015) and KAMIR-V (January, 2016 to June, 2020), we selected a total of 1833 patients (6.
Early identification of women at high risk for cardiovascular diseases (CVD), with subsequent monitoring, will allow for improved clinical outcomes and generally better quality of life. This study aimed to identify the associations between early menopause, abnormal diastolic function, and clinical outcomes. This retrospective study included 795 menopausal women from is a nationwide, multicenter, registry of patients with suspected angina visiting outpatient clinic.
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- Postmenopausal women in a study were older on average than men, but had higher healthy cholesterol levels and lower smoking rates.
- Though men had a higher prevalence of significant coronary artery disease (b-CAD) and required more revascularization procedures, statistical analysis showed that sex did not significantly affect the likelihood of needing revascularization.
- Interestingly, the long-term cardiovascular outcomes were better for postmenopausal women compared to men, suggesting they respond well to optimal treatment despite being older at the start of the study.
Data on the impact of arterial stiffness on autonomic function are limited. We sought to investigate whether heart rate recovery (HRR), a predictor of autonomic function, is impaired in patients with increased arterial stiffness. A total of 475 participants (mean age 55.
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- This study examines how socioeconomic status (SES) affects patients with high risk for cardiovascular disease, particularly those with obstructive coronary artery disease (CAD) undergoing invasive procedures.
- It compares outcomes between low SES patients (medical aid beneficiaries) and high SES patients (national health insurance beneficiaries), finding that both groups had similar rates of obstructive CAD.
- However, low SES patients experienced significantly worse long-term cardiovascular events (20.2% vs. 16.2%) over a 3.5-year follow-up, highlighting the link between socioeconomic disadvantage and poorer cardiovascular health outcomes.
Background: To make good use of the prognostic value of arterial stiffness, it is important to identify the population with the greatest benefit. In this study, we compared the prognostic value of brachial-ankle pulse wave velocity (baPWV) according to various clinical characteristics.
Methods: A total of 10,597 subjects who underwent baPWV measurement (mean age, 61.
Aims: This study evaluated the sex differences of sequential changes in coronary blood flows and microvascular function in patients with suspected angina but with no obstructed coronary arteries.
Methods: A total of 202 consecutive patients who experienced chest pain but had no significant coronary artery stenosis and who underwent adenosine stress echocardiography were included in the study. Coronary blood flow (CBF) velocities were measured at 1, 2, and 3 min after adenosine infusion.
Background/aims: Sex differences in the prognosis of heart failure (HF) have yielded inconsistent results, and data from Asian populations are even rare. This study aimed to investigate sex differences in clinical characteristics and long-term prognosis among Korean patients with HF.
Methods: A total of 5,625 Korean patients hospitalized for acute HF were analyzed using a prospective multi-center registry database.
Data on the relationship between arterial pulsatile hemodynamics and aortic root geometry, using invasive hemodynamic measurement, has been scarce. Thus, this study aimed to assess the relationship between invasively measured aortic pulse pressure (aPP) and the diameter of ascending aorta (AoD). We analyzed 665 subjects (64.
View Article and Find Full Text PDFBackground: Individuals of low socioeconomic status (SES) often exhibit increased cardiovascular risk factors and a worse prognosis. We conducted this study to ascertain whether brachial-ankle pulse wave velocity (baPWV), a straightforward and reliable measure of arterial stiffness, can hold prognostic value for people with low SES.
Methods: We retrospectively analyzed a total of 1266 subjects (mean age 64.
The correlation between body fat parameters and arterial stiffness is still under debate. This study aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with estimated pulse wave velocity (ePWV). We utilized data from 14,228 subjects (mean age 53.
View Article and Find Full Text PDFInterest in sex differences in coronary artery disease (CAD) has been steadily increasing. Concurrently, most of the data on these differences have primarily been Western-oriented. The KoRean wOmen'S chest pain rEgistry (KoROSE), started in 2011, has since published numerous research findings.
View Article and Find Full Text PDFBackground The prognostic value of estimated pulse wave velocity (ePWV) has been infrequently explored in high-risk patient groups. Our study aimed to evaluate the prognostic significance of ePWV among patients undergoing a percutaneous coronary intervention (PCI) with a drug-eluting stent (DES). Methods A total of 4119 consecutive subjects who underwent a PCI with a DES (mean age, 67.
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- A study was conducted on 1013 Korean patients without diabetes who underwent percutaneous coronary intervention (PCI) to analyze the impact of statin intensity on the development of new onset diabetes mellitus (NODM).
- Patients were treated with either high-intensity or moderate-intensity statins, revealing that those on high-intensity statins had a higher incidence of NODM (8.3%) compared to those on moderate-intensity statins (4.5%).
- Despite the increased risk of NODM, there were no significant differences in cardiovascular outcomes between the two groups, suggesting that a different approach to statin therapy might improve treatment efficacy without the safety concerns linked to NODM.
Background: Pregnancy increases long-term cardiovascular risk after childbirth, but the mechanisms are unclear. This study was performed to investigate the association between the number of pregnancies and several cardiac target organ damage (TOD) in middle-aged and elderly women.
Methods: Using the database of the nation-wide registry, a total of 1,137 women (mean age 63.
Background: Although the current guideline recommends the use of high-intensity statin to reduce the low-density lipoprotein cholesterol (LDL-C) level by 50% in patients with baseline value of ≥ 190 mg/dL, direct application of this recommendation to Asian populations is still questionable. This study was performed to investigate the statin response of LDL-C in Korean patients with LDL-C ≥ 190 mg/dL.
Methods: A total of 1,075 Korean patients (age 60.
Background: Little is known about the characteristics of arterial stiffness in heart failure (HF). This study was performed to compare the degree of arterial stiffness and its association with left ventricular (LV) diastolic function among three groups: control subjects, patients with HF with reduced ejection fraction (HFrEF), and patients with HF with preserved ejection fraction (HFpEF).
Methods: A total of 83 patients with HFrEF, 68 patients with HFpEF, and 84 control subjects were analyzed.
Article Synopsis
- The study aimed to analyze the characteristics of blood vessel connections in macular neovascularization (MNV) related to age-related macular degeneration using optical imaging, particularly focused on how often patients received injections.
- Researchers categorized 86 patients into two groups based on the number of injections in a year: stable (less than 3 injections) and unstable (3 or more injections) and examined various measurements of the anastomotic areas.
- Findings indicated that eyes with unstable condition had significantly larger anastomotic areas and longer diameters, suggesting that these characteristics may help determine the need for further treatment in patients with MNV.
Objective: The prognostic value of changes in arterial stiffness has not been well evaluated. This study was conducted to investigate whether the change in arterial stiffness one month after percutaneous coronary intervention (PCI) affects the long-term cardiovascular prognosis.
Methods: A total of 405 patients (mean age, 62.
The prognostic value of arterial stiffness in patients with diabetes mellitus (DM) remains unclear. The aim of this study was to investigate the association between brachial-ankle pulse wave velocity (baPWV) and the occurrence of cardiovascular events in people with DM. A total of 2714 subjects (mean age, 63.
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- This study examines the link between arterial stiffness and left ventricular diastolic function by analyzing a large sample of 7,013 participants, aged around 60 years.
- Significant correlations were found between arterial stiffness (measured by baPWV) and various diastolic function indicators, suggesting that higher stiffness is related to worse heart function.
- The findings reinforce existing research, demonstrating that increased arterial stiffness is tied to abnormal diastolic function, highlighting the importance of ventricular-vascular relationships in cardiovascular health.
Correction: Assessment of clinical effect and treatment quality of immediate-release carvedilol-IR versus SLOW release carvedilol-SR in Heart Failure patients (SLOW-HF): study protocol for a randomized controlled trial.
Trials
July 2022
Article Synopsis
- The study examines the relationship between the morphology of en face Haller vessels and macular neovascularization (MNV) and their impact on injection frequency and visual outcomes in patients with neovascular age-related macular degeneration (nAMD).
- Researchers analyzed optical coherence tomography (OCT) images from 52 eyes at different stages of treatment, focusing on various vascular metrics.
- Findings indicate that the length of Haller vessels correlates with injection frequency, and the size of MNV is linked to visual improvement, suggesting that these factors can serve as biomarkers for predicting treatment response in nAMD patients.