Publications by authors named "Mythili Ayyagari"

Article Synopsis
  • - Glucocorticoid (GC) therapy can effectively treat serious inflammatory disorders but carries risks of side effects, requiring the lowest effective dose for the shortest duration to minimize these risks.
  • - Tapering GC therapy is crucial to avoid adrenal insufficiency by allowing the hypothalamic-pituitary-adrenal (HPA) axis to recover while monitoring for disease reactivation; higher doses can be tapered quickly, but once close to physiologic doses, tapering must slow down.
  • - Patients on GCs need to be aware of potential adrenal crisis during illnesses and should increase their doses accordingly while carrying a steroid alert card to inform healthcare providers.
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Background: Ewing sarcoma (ES) with ectopic adrenocorticotropic hormone (ACTH) syndrome (ectopic ACTH) is extremely unusual. This report details the first case in English literature of pediatric ES involving the proximal aspect of the humerus with florid ectopic ACTH.

Case Report: A 9-year-old girl presented with mooning of the face and abdominal distension for the past 5 months with an unremarkable history.

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Context: Data on insulin usage and practices in children and adolescents with type 1 diabetes (T1D) is sparse in India.

Aims: To analyze the various insulin types and regimens used by children and adolescents with T1D, the techniques and the devices used for insulin administration, and the storage and disposal methods of delivery devices.

Settings And Design: Observational cross-sectional study.

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Context: Radioactive Iodine (RAI) is a common therapy for hyperthyroidism. However hyperthyroidism recurs or persists in 15-18% of patients after RAI. Studies report variable percentage of failure after RAI therapy depending on several variables including I(131).

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Introduction: Women with epilepsy (WWE) have an increased risk for several endocrine disorders. Obesity and Polycystic Ovarian Syndrome (PCOS) are common side-effects of anticonvulsant drugs.

Aim: To study the prevalence of Obesity, PCOS, Thyroid dysfunction in WWE on monotherapy with Carbamazepine (CBZ), Sodium Valproate (VAL) and Phenytoin (DPH) MATERIAL AND METHODS: Sixty WWE in the reproductive age group (13 - 45 yr) who are on atleast 6 months of monotherapy with either CBZ (20) or VAL (20) or DPH (20) are subjects of the study.

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